John M Higgins
Overview
Explore the profile of John M Higgins including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
4662
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Recent Articles
11.
Patel N, Tozzo V, Higgins J, Stone J
Arthritis Rheumatol
. 2022 Nov;
75(4):586-594.
PMID: 36383175
Objective: To study the longitudinal effects of both glucocorticoids and tocilizumab, an interleukin-6 receptor inhibitor, on hemoglobin A (HbA ) levels during glucocorticoid tapering. Methods: We analyzed patients with complete...
12.
Miller P, Fell G, Foy B, Scherer A, Gibson C, Sperling A, et al.
Blood
. 2022 Sep;
140(18):1993-1997.
PMID: 36096050
No abstract available.
13.
Foy B, Sundt T, Carlson J, Aguirre A, Higgins J
Nat Commun
. 2022 Aug;
13(1):4705.
PMID: 35995789
Inflammation is the physiologic reaction to cellular and tissue damage caused by trauma, ischemia, infection, and other pathologic conditions. Elevation of white blood cell count (WBC) and altered levels of...
14.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol
. 2022 Jun;
23(8):1285.
PMID: 35705799
No abstract available.
15.
Truslow J, Goto S, Homilius M, Mow C, Higgins J, MacRae C, et al.
Circ Cardiovasc Qual Outcomes
. 2022 Apr;
15(6):e008007.
PMID: 35477255
Background: Researchers routinely evaluate novel biomarkers for incorporation into clinical risk models, weighing tradeoffs between cost, availability, and ease of deployment. For risk assessment in population health initiatives, ideal inputs...
16.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol
. 2022 Mar;
23(4):605-618.
PMID: 35352063
Autonomic nerves control organ function through the sympathetic and parasympathetic branches, which have opposite effects. In the bone marrow, sympathetic (adrenergic) nerves promote hematopoiesis; however, how parasympathetic (cholinergic) signals modulate...
17.
Szafraniec H, Valdez J, Iffrig E, Lam W, Higgins J, Pearce P, et al.
Lab Chip
. 2022 Mar;
22(8):1565-1575.
PMID: 35315465
Characterization of blood flow rheology in hematological disorders is critical for understanding disease pathophysiology. Existing methods to measure blood rheological parameters are limited in their physiological relevance, and there is...
18.
Perazzo A, Peng Z, Young Y, Feng Z, Wood D, Higgins J, et al.
Soft Matter
. 2021 Dec;
18(3):554-565.
PMID: 34931640
Sickle cell anemia (SCA) is a disease that affects red blood cells (RBCs). Healthy RBCs are highly deformable objects that under flow can penetrate blood capillaries smaller than their typical...
19.
Geisness A, Azul M, Williams D, Szafraniec H, De Souza D, Higgins J, et al.
Haematologica
. 2021 Oct;
107(6):1438-1447.
PMID: 34706495
Sickle cell disease (SCD) is characterized by sickle hemoglobin (HbS) which polymerizes under deoxygenated conditions to form a stiff, sickled erythrocyte. The dehydration of sickle erythrocytes increases intracellular HbS concentration...
20.
Foy B, Sundt T, Carlson J, Aguirre A, Higgins J
medRxiv
. 2021 Jun;
PMID: 34189534
Inflammation is the physiologic reaction to cellular and tissue damage caused by pathologic processes including trauma, infection, and ischemia . Effective inflammatory responses integrate molecular and cellular functions to prevent...