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John M Hawdon

Explore the profile of John M Hawdon including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 831
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Recent Articles
1.
Jackson C, McKean E, Hawdon J
MicroPubl Biol . 2025 Jan; 2024. PMID: 39776753
This study explores potential small animal models for the dog hookworm, , a parasitic nematode which has repeatedly exhibited the ability to develop resistance to a range of anthelmintics. Immunomodulated...
2.
Herzog K, Wu R, Hawdon J, Nejsum P, Fauver J
iScience . 2024 Aug; 27(9):110614. PMID: 39211578
In this study, we assessed the quality of genome assemblies for three species of parasitic nematodes (, , and ) generated using only Oxford Nanopore Technologies MinION data. Assemblies were...
3.
McKean E, Grill E, Choi Y, Mitreva M, OHalloran D, Hawdon J
Parasitology . 2024 Jan; 151(3):271-281. PMID: 38163962
Parasitic gastrointestinal nematodes pose significant health risks to humans, livestock, and companion animals, and their control relies heavily on the use of anthelmintic drugs. Overuse of these drugs has led...
4.
Langeland A, McKean E, OHalloran D, Hawdon J
Parasitology . 2023 Nov; 151(1):102-107. PMID: 38018393
Hookworm infection affects millions globally, leading to chronic conditions like malnutrition and anaemia. Among the hookworm species, stands out as a generalist, capable of infecting various hosts, including humans, cats,...
5.
Langeland A, Grill E, Shetty A, OHalloran D, Hawdon J
Parasitology . 2023 Mar; 150(6):511-523. PMID: 36883013
Soil-transmitted nematodes (STNs) place a tremendous burden on health and economics worldwide with an estimate of at least 1.5 billion people, or 24% of the population, being infected with at...
6.
Uzoechi S, Rosa B, Singh K, Choi Y, Bracken B, Brindley P, et al.
Pathogens . 2023 Jan; 12(1). PMID: 36678443
The dynamic host-parasite mechanisms underlying hookworm infection establishment and maintenance in mammalian hosts remain poorly understood but are primarily mediated by hookworm's excretory/secretory products (ESPs), which have a wide spectrum...
7.
Huynh T, McKean E, Hawdon J
J Parasitol . 2022 Aug; 108(4):403-407. PMID: 36027574
The Baermann filter method is a long-standing, simple technique for recovering nematodes from soil and charcoal coprocultures. Material containing the nematodes is placed on a mesh screen lined with several...
8.
Heryanto C, Ratnappan R, OHalloran D, Hawdon J, Eleftherianos I
J Vis Exp . 2022 Apr; (181). PMID: 35435903
Entomopathogenic nematodes in the genera Heterorhabditis and Steinernema are obligate parasites of insects that live in the soil. The main characteristic of their life cycle is the mutualistic association with...
9.
Pritchard D, Diemert D, Bottazzi M, Hawdon J, Correa-Oliveira R, Bethony J
Curr Top Microbiol Immunol . 2021 Jul; 445:367-377. PMID: 34328562
In this chapter, we describe the scientific, technical, clinical and regulatory aspects of establishing a controlled human hookworm infection (CHHI) model in non-endemic and endemic geographical regions, to facilitate a...
10.
Motaher R, Grill E, McKean E, Kenney E, Eleftherianos I, Hawdon J, et al.
Comput Biol Chem . 2021 Mar; 92:107464. PMID: 33667976
Parasitic nematodes constitute one of the major threats to human health, causing diseases of major socioeconomic importance worldwide. Recent estimates indicate that more than 1 billion people are infected with...