John M Gansner
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Explore the profile of John M Gansner including associated specialties, affiliations and a list of published articles.
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29
Citations
808
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Recent Articles
11.
Kennedy A, Myers K, Bowman J, Gibson C, Camarda N, Furutani E, et al.
Nat Commun
. 2021 Feb;
12(1):1334.
PMID: 33637765
To understand the mechanisms that mediate germline genetic leukemia predisposition, we studied the inherited ribosomopathy Shwachman-Diamond syndrome (SDS), a bone marrow failure disorder with high risk of myeloid malignancies at...
12.
Zhao J, Gabriel E, Norda R, Hoglund P, Baden L, Diedrich B, et al.
Transfusion
. 2020 Nov;
61(2):464-473.
PMID: 33186486
Background: Recently, plateletpheresis donations using a widely used leukoreduction system (LRS) chamber have been associated with T-cell lymphopenia. However, clinical health consequences of plateletpheresis-associated lymphopenia are still unknown. Study Design...
13.
Gansner J, Papari M, Goldstein J, Gaufberg R, Neuberg D, Makar R, et al.
Transfusion
. 2019 Jul;
59(9):2783-2787.
PMID: 31271458
Background: In a recent study, we determined that 30% of frequent plateletpheresis donors collected using the Trima Accel Automated Blood Collection System (Terumo BCT) had a CD4+ T-cell count below...
14.
Rahmani M, Fortin B, Berliner N, Issa N, Neuberg D, Kaufman R, et al.
Transfusion
. 2019 Feb;
59(5):1644-1647.
PMID: 30747442
Background: We recently discovered that 30% of current frequent apheresis platelet donors in a study at our donor center had CD4+ counts below 200 cells/μL. How long CD4+ lymphopenia persists...
15.
Gansner J, Berliner N
Hematology Am Soc Hematol Educ Program
. 2018 Dec;
2018(1):313-317.
PMID: 30504326
Catastrophic antiphospholipid antibody syndrome (CAPS) and macrophage activation syndrome (MAS) are both life-threatening hematologic disorders that infrequently afflict patients with rheumatologic disease. CAPS is characterized by fulminant multiorgan damage related...
16.
Gansner J, Rahmani M, Jonsson A, Fortin B, Brimah I, Ellis M, et al.
Blood
. 2018 Nov;
133(6):605-614.
PMID: 30429159
More than 1 million apheresis platelet collections are performed annually in the United States. After 2 healthy plateletpheresis donors were incidentally found to have low CD4 T-lymphocyte counts, we investigated...
17.
Kapp F, Perlin J, Hagedorn E, Gansner J, Schwarz D, OConnell L, et al.
Nature
. 2018 Jun;
558(7710):445-448.
PMID: 29899448
Haematopoietic stem and progenitor cells (HSPCs) require a specific microenvironment, the haematopoietic niche, which regulates HSPC behaviour. The location of this niche varies across species, but the evolutionary pressures that...
18.
Gansner J, Furutani E, Campagna D, Fleming M, Shimamura A
Am J Hematol
. 2018 Jun;
93(9):1194-1195.
PMID: 29885000
No abstract available.
19.
Gansner J, Achebe M, Gray K, Yefidoff-Freedman R, Labovitis E, Parnes A, et al.
Blood
. 2017 Aug;
130(14):1671-1674.
PMID: 28798157
No abstract available.
20.
Bendapudi P, Hurwitz S, Fry A, Marques M, Waldo S, Li A, et al.
Lancet Haematol
. 2017 Mar;
4(4):e157-e164.
PMID: 28259520
Background: Among the syndromes characterised by thrombotic microangiopathy, thrombotic thrombocytopenic purpura is distinguished by a severe deficiency in the ADAMTS13 enzyme. Patients with this disorder need urgent treatment with plasma...