John Linley
Overview
Explore the profile of John Linley including associated specialties, affiliations and a list of published articles.
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2
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18
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Recent Articles
1.
Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis
Al-Hazza A, Linley J, Aziz Q, Hunter M, Sandle G
Biochem Biophys Res Commun
. 2016 Jan;
470(2):473-478.
PMID: 26718405
Background: Basolateral K(+) channels hyperpolarize colonocytes to ensure Na(+) (and thus water) absorption. Small conductance basolateral (KCNQ1/KCNE3) K(+) channels have never been evaluated in human colon. We therefore evaluated KCNQ1/KCNE3...
2.
Linley J, Loganathan A, Kopanati S, Sandle G, Hunter M
Gut
. 2013 Jun;
63(3):472-9.
PMID: 23740188
Background: Human colon may secrete substantial amounts of water secondary to chloride (Cl(-)) and/or potassium (K(+)) secretion in a variety of diarrhoeal diseases. Ion secretion occurs via Cl(-) and K(+)...