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John Kolbe

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Articles 55
Citations 564
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Recent Articles
1.
Chen C, Kolbe J, Paton J, Fisher J
Exp Physiol . 2024 Oct; 110(1):15-22. PMID: 39395197
Exercise intolerance and exertional dyspnoea are hallmarks of fibrosing interstitial lung disease (FILD) and are associated with worse prognosis and quality of life. Activation of pulmonary vagal afferents influences the...
2.
Chen C, Kolbe J, Paton J, Fisher J
Respir Med Res . 2024 Apr; 85:101103. PMID: 38663251
Background: Exertional dyspnoea, a cardinal symptom in interstitial lung disease (ILD), can be objectively measured during a 6-min walk test (6MWT) using the Borg Dyspnoea Score (BDS). However, the clinical...
3.
Jayasimhan D, Chieng J, Kolbe J, Sidebotham D
Crit Care Med . 2023 May; 51(10):1363-1372. PMID: 37204257
Objectives: Acute respiratory distress syndrome (ARDS) is associated with high ventilation-perfusion heterogeneity and dead-space ventilation. However, whether the degree of dead-space ventilation is associated with outcomes is uncertain. In this...
4.
Jayasimhan D, Welch R, Ellyett K, Pasley T, Kolbe J
Clin Transplant . 2023 Mar; 37(4):e14973. PMID: 36938712
Cardiopulmonary exercise testing is commonly used to evaluate patients for heart transplantation. We assessed the utility of ventilatory efficiency (VE/VCO ) to predict perioperative outcomes following heart transplantation. We retrospectively...
5.
Welch R, Lardenoye M, Kolbe J, Ellyett K
J Asthma . 2022 Sep; 60(5):1016-1023. PMID: 36066117
Objective: There are few studies in clinically healthy subjects describing and quantifying exercise-induced bronchodilation (EIB). This study aimed to describe and compare the magnitude and time course changes in post-exercise...
6.
Chen C, Kolbe J, Wilsher M, de Boer S, Paton J, Fisher J
Exp Physiol . 2022 Mar; 107(5):527-540. PMID: 35298060
New Findings: What is the central question of this study? We determined whether sensory feedback from metabolically sensitive skeletal muscle afferents (metaboreflex) causes a greater ventilatory response and higher dyspnoea...
7.
Welch R, Francis A, Babbage T, Lardenoye M, Kolbe J, Ellyett K
Physiol Meas . 2021 Dec; 42(11). PMID: 34874285
. Tidal expiratory flow limitation (EFL) is commonly identified by tidal breaths exceeding the forced vital capacity (FVC) loop. This technique, known as the Hyatt method, is limited by the...
8.
Kolbe J
Pol Arch Intern Med . 2021 Nov; 132(1). PMID: 34779191
While bronchiectasis is an old condition, it is only in the last decade that there have been major strides in our understanding of this disease and its treatment. Recent evidence...
9.
Chen C, Kolbe J, Christmas T
Intern Med J . 2021 Apr; 51(4):596-599. PMID: 33890378
Lung resection in patients aged ≥80 years is considered high risk and contributes to the low rates of resection in this population. This review of 79 octogenarians who underwent curative...
10.
Welch R, Kolbe J, Lardenoye M, Ellyett K
Physiol Meas . 2021 Mar; 42(4). PMID: 33740782
Exercise oscillatory ventilation (EOV) is frequently observed in individuals with cardiac disease. Assessment of EOV relies on pattern recognition and this subjectivity and lack of quantification limits the widespread clinical...