John K Hurley
Overview
Explore the profile of John K Hurley including associated specialties, affiliations and a list of published articles.
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14
Citations
322
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Recent Articles
1.
Zhang W, Hubbard A, Jones T, Racolta A, Bhaumik S, Cummins N, et al.
Lab Invest
. 2017 May;
97(7):873-885.
PMID: 28504684
The ability to simultaneously visualize the presence, abundance, location and functional state of many targets in cells and tissues has been described as a true next-generation approach in immunohistochemistry (IHC)....
2.
Hurley J, Silverstein D
Curr Pediatr Rev
. 2014 Aug;
10(2):87.
PMID: 25088260
No abstract available.
3.
Mirza M, Shaughnessy E, Hurley J, Vanpatten K, Pestano G, He B, et al.
Int J Cancer
. 2007 Oct;
122(4):889-97.
PMID: 17960616
While the acquisition of invasiveness is a critical step in early stage breast carcinomas (DCIS), no established molecular markers reliably identify tumor progression. The metastasis gene osteopontin is subject to...
4.
Cho M, Hurley J, Kopp J
Am J Kidney Dis
. 2007 Jan;
49(2):310-7.
PMID: 17261434
To evaluate the safety and efficacy of sirolimus in treating patients with focal segmental glomerulosclerosis (FSGS), we performed a phase 2, open-label clinical trial. Inclusion criteria were adults and children...
5.
Rao V, Dugan F, Dale J, Davis J, Tretler J, Hurley J, et al.
Br J Haematol
. 2005 May;
129(4):534-8.
PMID: 15877736
Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of apoptosis associated most often with heritable FAS mutations leading to lymphadenopathy, hypersplenism and chronic refractory autoimmune cytopenias. Mycophenolate mofetil (MMF) was used...
6.
Nogues I, Tejero J, Hurley J, Paladini D, Frago S, Tollin G, et al.
Biochemistry
. 2004 May;
43(20):6127-37.
PMID: 15147197
The catalytic mechanism proposed for ferredoxin-NADP(+) reductase (FNR) is initiated by reduction of its flavin adenine dinucleotide (FAD) cofactor by the obligatory one-electron carriers ferredoxin (Fd) or flavodoxin (Fld) in...
7.
Hirasawa M, Rubio L, Griffin J, Flores E, Herrero A, Li J, et al.
Biochim Biophys Acta
. 2004 Feb;
1608(2-3):155-62.
PMID: 14871493
The ferredoxin-dependent nitrate reductase from the cyanobacterium Synechococcus sp. PCC 7942 has been shown to form a high-affinity complex with ferredoxin at low ionic strength. This complex, detected by changes...
8.
Feng C, Wilson H, Hurley J, Hazzard J, Tollin G, Rajagopalan K, et al.
Biochemistry
. 2003 Oct;
42(42):12235-42.
PMID: 14567685
Arginine 160 in human sulfite oxidase (SO) is conserved in all SO species sequenced to date. Previous steady-state kinetic studies of the R160Q human SO mutant showed a remarkable decrease...
9.
Tejero J, Martinez-Julvez M, Mayoral T, Luquita A, Sanz-Aparicio J, Hermoso J, et al.
J Biol Chem
. 2003 Sep;
278(49):49203-14.
PMID: 14500716
Previous studies indicated that the determinants of coenzyme specificity in ferredoxin-NADP+ reductase (FNR) from Anabaena are situated in the 2'-phosphate (2'-P) NADP+ binding region, and also suggested that other regions...
10.
Nogues I, Martinez-Julvez M, Navarro J, Hervas M, Armenteros L, Angel De la Rosa M, et al.
Biochemistry
. 2003 Feb;
42(7):2036-45.
PMID: 12590591
Hydrophobic interactions play an active role in effective complex formation between ferredoxin-NADP(+) reductase (FNR) and ferredoxin (Fd) from Anabaena, where an aromatic amino acid residue on the Fd surface (F65)...