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John J McCarthy

Explore the profile of John J McCarthy including associated specialties, affiliations and a list of published articles. Areas
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Articles 132
Citations 5205
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Recent Articles
1.
Delisle B, Prabhat A, Burgess D, Stumpf I, McCarthy J, Procopio S, et al.
J Mol Cell Cardiol . 2025 Jan; 200:93-112. PMID: 39864795
Cardiologists have analyzed daily patterns in the incidence of sudden cardiac death to identify environmental, behavioral, and physiological factors that trigger fatal arrhythmias. Recent studies have indicated an overall increase...
2.
Burke B, Ismaeel A, Long D, Depa L, Coburn P, Goh J, et al.
JCI Insight . 2024 Sep; 9(21). PMID: 39316445
Extracellular vesicles (EVs) have emerged as important mediators of intertissue signaling and exercise adaptations. In this human study, we provide evidence that muscle-specific microRNA-1 (miR-1) was transferred to adipose tissue...
3.
Ismaeel A, Peck B, Montgomery M, Burke B, Goh J, Kang G, et al.
bioRxiv . 2024 Aug; PMID: 39149347
MicroRNA-1 (miR-1) is the most abundant miRNA in adult skeletal muscle. To determine the function of miR-1 in adult skeletal muscle, we generated an inducible, skeletal muscle-specific miR-1 knockout (KO)...
4.
Saliu T, Goh J, Kang G, Burke B, Ismaeel A, McCarthy J
Biochem Soc Trans . 2024 Aug; 52(4):1921-1926. PMID: 39136196
Skeletal muscle stem cells (MuSCs) display distinct behavior crucial for tissue maintenance and repair. Upon activation, MuSCs exhibit distinct modes of division: symmetric division, facilitating either self-renewal or differentiation, and...
5.
Burke B, Ismaeel A, von Walden F, Murach K, McCarthy J
Am J Physiol Cell Physiol . 2024 Jul; 327(3):C614-C618. PMID: 39069829
Roberts et al. have provided an insightful counterpoint to our review article on the utility of the synergist ablation model. The purpose of this review is to provide some further...
6.
Burke B, Ismaeel A, McCarthy J
Am J Physiol Cell Physiol . 2024 Jul; 327(3):C601-C606. PMID: 39069822
Skeletal muscle exhibits remarkable plasticity to adapt to stimuli such as mechanical loading. The mechanisms that regulate skeletal muscle hypertrophy due to mechanical overload have been thoroughly studied. Remarkably, our...
7.
Valentino T, Burke B, Kang G, Goh J, Dungan C, Ismaeel A, et al.
bioRxiv . 2024 Jun; PMID: 38854012
Regular exercise yields a multitude of systemic benefits, many of which may be mediated through the gut microbiome. Here, we report that cecal microbial transplants (CMTs) from exercise-trained vs. sedentary...
8.
McCarthy J, Finnegan L
Front Pediatr . 2024 Jan; 11:1316583. PMID: 38188918
Since the first use of methadone to treat OUD in pregnancy in the 1970s, there has been a long, controversial, and confusing history of studies, regulatory actions, and practice changes...
9.
Burke B, Goh J, Albathi F, Valentino T, Nolt G, Joshi J, et al.
Front Physiol . 2023 Dec; 14:1302695. PMID: 38074327
Apolipoprotein E (ApoE) has been shown to be necessary for proper skeletal muscle regeneration. Consistent with this finding, single-cell RNA-sequencing analyses of skeletal muscle stem cells (MuSCs) revealed that is...
10.
Ismaeel A, Goh J, Mobley C, Murach K, Brett J, de Morree A, et al.
Stem Cells . 2023 Dec; 42(3):266-277. PMID: 38066665
Adult muscle stem cells (MuSCs) are known to replicate upon activation before differentiating and fusing to regenerate myofibers. It is unclear whether MuSC differentiation is intrinsically linked to cell division,...