John J Lima
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Explore the profile of John J Lima including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
2005
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Recent Articles
1.
Lang J, Hossain J, Blake K, Mercado A, Lima J
Pediatr Allergy Immunol Pulmonol
. 2022 Aug;
26(1):11-17.
PMID: 35927845
Roughly 9% of African-Americans carry 1 copy of the sickle β-globin allele [sickle-cell trait (SCT)]. The sickle allele may affect the host responses in a way that protects against sequelae...
2.
Ortega V, Daya M, Szefler S, Bleecker E, Chinchilli V, Phipatanakul W, et al.
Lancet Child Adolesc Health
. 2021 Nov;
5(12):862-872.
PMID: 34762840
Background: Pharmacogenetic studies in asthma cohorts, primarily made up of White people of European descent, have identified loci associated with response to inhaled beta agonists and corticosteroids (ICSs). Differences exist...
3.
Lima J, Thomas C, Barbarino J, Desta Z, Van Driest S, El Rouby N, et al.
Clin Pharmacol Ther
. 2020 Aug;
109(6):1417-1423.
PMID: 32770672
Proton pump inhibitors (PPIs) are widely used for acid suppression in the treatment and prevention of many conditions, including gastroesophageal reflux disease, gastric and duodenal ulcers, erosive esophagitis, Helicobacter pylori...
4.
Bernal C, Aka I, Carroll R, Coco J, Lima J, Acra S, et al.
Pediatrics
. 2019 Nov;
144(6).
PMID: 31699831
Objectives: Proton pump inhibitors (PPIs) are often used in pediatrics to treat common gastrointestinal disorders, and there are growing concerns for infectious adverse events. Because CYP2C19 inactivates PPIs, genetic variants...
5.
Wechsler M, Szefler S, Ortega V, Pongracic J, Chinchilli V, Lima J, et al.
N Engl J Med
. 2019 Sep;
381(13):1227-1239.
PMID: 31553835
Background: Morbidity from asthma is disproportionately higher among black patients than among white patients, and black patients constitute the minority of participants in trials informing treatment. Data indicate that patients...
6.
Mougey E, Williams A, Kunz Coyne A, Gutierrez-Junquera C, Fernandez-Fernandez S, Cilleruelo M, et al.
J Pediatr Gastroenterol Nutr
. 2019 Sep;
69(5):581-587.
PMID: 31490856
Objective: Proton pump inhibitors (PPIs) are an effective treatment for eosinophilic esophagitis (EoE); however, only 30% to 60% of patients respond. Common genetic variants in CYP2C19 and STAT6 associate with...
7.
Lang J, Bunnell H, Lima J, Hossain M, Wysocki T, Bacharier L, et al.
Pediatr Pulmonol
. 2019 Aug;
54(11):1684-1693.
PMID: 31469258
Rationale: Obesity in children increases the risk for new asthma. How age, sex, race/ethnicity, and allergy status affect the relationship between obesity and asthma is unclear. This study describes the...
8.
Lang J, Mougey E, Hossain M, Livingston F, Babu Balagopal P, Langdon S, et al.
Ann Am Thorac Soc
. 2019 Jan;
16(5):554-562.
PMID: 30678465
Omega-3 fatty acid (n3PUFA) supplementation has been proposed as a promising antiasthma strategy. The rs59439148 polymorphism affects leukotriene production and possibly inflammatory responses to n3PUFA. Assess the effects of n3PUFA...
9.
Tang M, Blake K, Lima J, Mougey E, Franciosi J, Schmidt S, et al.
Contemp Clin Trials
. 2019 Jan;
78:27-33.
PMID: 30659924
Asthma causes enormous suffering and cost for children in the US and around the world [1-3]. Co-morbid gastroesophageal reflux disease (GERD) makes asthma management more difficult due to increased symptoms....
10.
Pereira A, Pollard S, Locke R, Romero K, Lima J, Hansel N, et al.
Respir Med
. 2018 Dec;
145:212-216.
PMID: 30509712
Background: Asthma prevalence continues to increase in low and middle-income countries, presenting challenges in assessing asthma control in resource-poor settings. Previous studies suggest that exhaled carbon monoxide (eCO) is higher...