John Hallenbeck
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Explore the profile of John Hallenbeck including associated specialties, affiliations and a list of published articles.
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19
Citations
386
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Recent Articles
1.
Quandt J, Becquart P, Kamma E, Hallenbeck J
Front Mol Neurosci
. 2019 Sep;
12:190.
PMID: 31507371
E-selectin plays an important role in mediating the rolling of leukocytes along and thus, the subsequent extravasation across activated endothelial cells comprising the microvasculature of the blood brain barrier (BBB)....
2.
Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke
Choi S, Arai A, Mou Y, Kang B, Yen C, Hallenbeck J, et al.
Stroke
. 2018 Feb;
49(3):718-726.
PMID: 29440474
Background And Purpose: MAGL (monoacylglycerol lipase) is an enzyme that hydrolyzes the endocannabinoid 2-arachidonoylglycerol and regulates the production of arachidonic acid and prostaglandins-substances that mediate tissue inflammatory response. Here, we...
3.
Hollander M, Latour L, Yang D, Ishii H, Xiao Z, Min Y, et al.
Circ Res
. 2017 Oct;
121(12):1360-1369.
PMID: 29051340
Rationale: Cryptogenic strokes, those of unknown cause, have been estimated as high as 30% to 40% of strokes. Inflammation has been suggested as a critical etiologic factor. However, there is...
4.
Bogoslovsky T, Maric D, Gong Y, Qu B, Yang K, Spatz M, et al.
Biomark Med
. 2015 Jul;
9(7):625-37.
PMID: 26174838
Aims: Endothelial progenitor cells (EPCs) are markers of vascular repair. Increased numbers of circulating endothelial cells (ECs) are associated with endothelial damage. Materials & Methods: We enumerated EPC-EC by using...
5.
Bielekova B, Vodovotz Y, An G, Hallenbeck J
Front Neurol
. 2014 Jul;
5:102.
PMID: 25018747
Systems biology comprises a series of concepts and approaches that have been used successfully both to delineate novel biological mechanisms and to drive translational advances. The goal of systems biology...
6.
Castri P, Lee Y, Ponzio T, Maric D, Spatz M, Bembry J, et al.
Biochim Biophys Acta
. 2013 Dec;
1843(3):640-51.
PMID: 24333653
Poly(ADP-ribose) polymerase-1 (PARP-1) and its cleavage products regulate cell viability and NF-kappaB activity when expressed in neurons. PARP-1 cleavage generates a 24 kDa (PARP-1(24)) and an 89 kDa fragment (PARP-1(89))....
7.
Famakin B, Mou Y, Johnson K, Spatz M, Hallenbeck J
J Cereb Blood Flow Metab
. 2013 Dec;
34(2):258-67.
PMID: 24301291
To better understand the role of downstream Toll-like receptor (TLR) signaling during acute cerebral ischemia, we performed cDNA microarrays, on brain RNA, and cytokine arrays, on serum, from wild type...
8.
Famakin B, Mou Y, Spatz M, Lawal M, Hallenbeck J
J Neuroinflammation
. 2012 Jul;
9:174.
PMID: 22799573
Background: Deletion of some Toll-like receptors (TLRs) affords protection against cerebral ischemia, but disruption of their known major downstream adaptors does not. To determine whether compensation in the production of...
9.
Hallenbeck J
Ann N Y Acad Sci
. 2010 Oct;
1207:1-7.
PMID: 20955418
I here describe a line of research that grew out of studies of spinal cord-damaging decompression sickness, focused on the blood-endothelial interface, that was influenced by the local Shwartzman phenomenon,...
10.
Nakayama T, Illoh K, Ruetzler C, Auh S, Sokoloff L, Hallenbeck J
Brain Res
. 2006 Dec;
1132(1):177-84.
PMID: 17188657
Evidence that inflammatory and immune mechanisms may have a critical role in the development of vasospasm after subarachnoid hemorrhage is accumulating. We examined, therefore, whether induction of immunological tolerance to...