» Authors » John H Weiss

John H Weiss

Explore the profile of John H Weiss including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 44
Citations 1578
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Medvedeva Y, Yin H, Bazrafkan A, Yeromin A, Ji S, Weiss-Hung E, et al.
J Neurosci . 2022 May; 42(26):5281-5292. PMID: 35623885
Zn is an important contributor to ischemic brain injury, and recent studies support the hypothesis that mitochondria are key sites of its injurious effects. In murine hippocampal slices (both sexes)...
2.
Granzotto A, Weiss J, Sensi S
Front Neurosci . 2022 Feb; 15:831809. PMID: 35110994
No abstract available.
3.
Liu H, Gale J, Reynolds I, Weiss J, Aizenman E
Biomedicines . 2021 May; 9(5). PMID: 33946782
Zinc is a highly abundant cation in the brain, essential for cellular functions, including transcription, enzymatic activity, and cell signaling. However, zinc can also trigger injurious cascades in neurons, contributing...
4.
Ji S, Medvedeva Y, Weiss J
Exp Neurol . 2019 Dec; 325:113161. PMID: 31881218
Excitotoxic Ca accumulation contributes to ischemic neurodegeneration, and Ca can enter the mitochondria through the mitochondrial calcium uniporter (MCU) to promote mitochondrial dysfunction. Yet, Ca-targeted therapies have met limited success....
5.
Yin H, Wang H, Ji S, Medvedeva Y, Tian G, Bazrafkan A, et al.
J Neuropathol Exp Neurol . 2019 Jun; 78(7):655-664. PMID: 31150090
Mitochondrial Zn2+ accumulation, particularly in CA1 neurons, occurs after ischemia and likely contributes to mitochondrial dysfunction and subsequent neurodegeneration. However, the relationship between mitochondrial Zn2+ accumulation and their disruption has...
6.
Ji S, Medvedeva Y, Wang H, Yin H, Weiss J
Neuroscientist . 2018 May; 25(2):126-138. PMID: 29742958
Ischemic stroke is a major cause of death and disabilities worldwide, and it has been long hoped that improved understanding of relevant injury mechanisms would yield targeted neuroprotective therapies. While...
7.
Ji S, Weiss J
Exp Neurol . 2018 Jan; 302:181-195. PMID: 29355498
Excitotoxic Zn and Ca accumulation contributes to neuronal injury after ischemia or prolonged seizures. Synaptically released Zn can enter postsynaptic neurons via routes including voltage sensitive Ca channels (VSCC), and,...
8.
Medvedeva Y, Ji S, Yin H, Weiss J
J Neurosci . 2017 Jan; 37(3):726-737. PMID: 28100752
Significance Statement: The basis for the differential vulnerabilities of CA1 versus CA3 pyramidal neurons is unclear. The present study of events during and after acute oxygen glucose deprivation highlights a...
9.
Li S, Kabeer M, Vu L, Keschrumrus V, Yin H, Dethlefs B, et al.
World J Stem Cells . 2014 Sep; 6(4):432-40. PMID: 25258664
The treatment of malignant brain tumors remains a challenge. Stem cell technology has been applied in the treatment of brain tumors largely because of the ability of some stem cells...
10.
Yin H, Yu S, Hsu C, Liu J, Acab A, Wu R, et al.
Exp Neurol . 2014 Jun; 261:1-9. PMID: 24918341
The neurotoxin beta-N-methylamino-l-alanine (BMAA) was first identified as a "toxin of interest" in regard to the amyotrophic lateral sclerosis-Parkinsonism Dementia Complex of Guam (ALS/PDC); studies in recent years highlighting widespread...