John H Saunders
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Explore the profile of John H Saunders including associated specialties, affiliations and a list of published articles.
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8
Citations
45
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Recent Articles
1.
Sharpe B, Hayden A, Manousopoulou A, Cowie A, Walker R, Harrington J, et al.
Cell Rep Med
. 2022 Jun;
3(6):100541.
PMID: 35732148
The chemotherapy resistance of esophageal adenocarcinomas (EACs) is underpinned by cancer cell extrinsic mechanisms of the tumor microenvironment (TME). We demonstrate that, by targeting the tumor-promoting functions of the predominant...
2.
Saunders J, Al-Zubaidi S, Waller R, Ortiz-Fernandez-Sordo J, Parsons S, Ragunath K, et al.
Dis Esophagus
. 2020 Feb;
33(9).
PMID: 32090253
Endoscopic resection (ER) for early (pT1) esophageal adenocarcinoma can be justified if the rate of coexisting lymph node (LN) metastasis is less than the mortality rate from esophagectomy. This study...
3.
Boucher A, Ng O, Saunders J, Acheson A, Parsons S
J Gastrointest Oncol
. 2018 Dec;
9(5):797-805.
PMID: 30505578
Background: Anaemia reduces the efficacy of chemotherapy in gastric cancer. However, it has not been studied in oesophageal cancer. We investigated whether anaemia impacts on survival and the efficacy of...
4.
Onion D, Isherwood M, Shridhar N, Xenophontos M, Craze M, Day L, et al.
Oncotarget
. 2018 Feb;
9(2):1760-1771.
PMID: 29416729
The complex interplay of the tumour microenvironment (TME) and its role in disease progression and response to therapy is poorly understood. The majority of studies to date focus on individual...
5.
Saunders J, Bowman C, Reece-Smith A, Pang V, Dorrington M, Mumtaz E, et al.
J Surg Oncol
. 2017 Mar;
115(7):821-829.
PMID: 28257148
Background And Objectives: For patients with operable esophagogastric cancer, peri-operative chemotherapy confers a significant overall survival benefit compared to surgery alone, however only 30-40% of patients demonstrate histopathological response. It...
6.
Saunders J, Onion D, Collier P, Dorrington M, Argent R, Clarke P, et al.
Oncotarget
. 2016 Oct;
8(15):24224-24236.
PMID: 27736801
Background: A model to predict chemotherapy response would provide a marked clinical benefit, enabling tailored treatment of oesophageal cancer, where less than half of patients respond to the routinely administered...
7.
Saunders J, Abisi S, Altaf N, Yong Y, MacSweeney S, Whittaker S, et al.
Cardiovasc Intervent Radiol
. 2013 Oct;
37(4):914-9.
PMID: 24091756
Purpose: Endovascular repair of popliteal artery aneurysms (PAA) has become increasingly popular; however, long-term patency and limb salvage rates are not fully established. Methods: A retrospective review of all endovascular...
8.
Matheson C, Matheson D, Saunders J, Howarth C
BMC Med Educ
. 2010 Jun;
10:48.
PMID: 20573253
Background: The UK General Medical Council recommends that medical students have the opportunity of shadowing the outgoing new doctor whose post they will soon undertake. At the University of Nottingham...