John H Moore
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Explore the profile of John H Moore including associated specialties, affiliations and a list of published articles.
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20
Citations
218
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Recent Articles
1.
Moore J, Salahi A, Honrado C, Warburton C, Tate S, Warren C, et al.
ACS Infect Dis
. 2023 Sep;
9(10):1878-1888.
PMID: 37756389
Antibiotic-induced microbiota disruption and its persistence create conditions for dysbiosis and colonization by opportunistic pathogens, such as those causing () infection (CDI), which is the most severe hospital-acquired intestinal infection....
2.
Honrado C, Salahi A, Adair S, Moore J, Bauer T, Swami N
Lab Chip
. 2022 Aug;
22(19):3708-3720.
PMID: 35997278
Unrestricted cell death can lead to an immunosuppressive tumor microenvironment, with dysregulated apoptotic signaling that causes resistance of pancreatic cancer cells to cytotoxic therapies. Hence, modulating cell death by distinguishing...
3.
Liu Y, Moore J, Harbaugh S, Chavez J, Chou C, Swami N
Mikrochim Acta
. 2021 Dec;
189(1):4.
PMID: 34855041
Synthetic biology approaches for rewiring of bacterial constructs to express particular intracellular factors upon induction with the target analyte are emerging as sensing paradigms for applications in environmental and in...
4.
Honrado C, Adair S, Moore J, Salahi A, Bauer T, Swami N
Adv Biol (Weinh)
. 2021 May;
5(8):e2100438.
PMID: 34015194
The ability to rapidly and sensitively predict drug response and toxicity using in vitro models of patient-derived tumors is essential for assessing chemotherapy efficacy. Currently, drug sensitivity assessment for solid...
5.
Honrado C, Michel N, Moore J, Salahi A, Porterfield V, McConnell M, et al.
ACS Sens
. 2020 Dec;
6(1):156-165.
PMID: 33325234
The ability to coax human-induced pluripotent stem cells (hiPSCs) into human neural progenitor cells (hNPCs) can lead to novel drug discovery and transplant therapy platforms for neurological diseases. Since hNPCs...
6.
Moore J, Salahi A, Honrado C, Warburton C, Warren C, Swami N
Biosens Bioelectron
. 2020 Aug;
166:112440.
PMID: 32745926
The germination of ingested spores is often a necessary first step required for enabling bacterial outgrowth and host colonization, as in the case of Clostridioides difficile (C. difficile) infection. Spore...
7.
Liu Y, Moore J, Kolling G, McGrath J, Papin J, Swami N
Sens Actuators B Chem
. 2020 Jul;
312.
PMID: 32606491
Infections due to () often exhibit broad-spectrum resistance and persistence to common antibiotics. Persistence is especially problematic with immune-compromised subjects who are unable to eliminate the inhibited bacteria. Hence, antibiotics...
8.
Moore J, Honrado C, Stagnaro V, Kolling G, Warren C, Swami N
ACS Infect Dis
. 2020 Apr;
6(5):1000-1007.
PMID: 32239920
() infection (CDI) is the primary cause of nosocomial antibiotic-associated diarrhea, with high recurrence rates following initial antibiotic treatment regimens. Restoration of the host gut microbiome through probiotic therapy is...
9.
Moore J, Varhue W, Su Y, Linton S, Farmehini V, Fox T, et al.
Anal Chem
. 2019 Jul;
91(16):10424-10431.
PMID: 31333013
Diagnostics based on exosomes and other extracellular vesicles (EVs) are emerging as strategies for informing cancer progression and therapies, since the lipid content and macromolecular cargo of EVs can provide...
10.
Rohani A, Moore J, Su Y, Stagnaro V, Warren C, Swami N
Sens Actuators B Chem
. 2018 Oct;
276:472-480.
PMID: 30369719
Current methods for measurement of antibiotic susceptibility of pathogenic bacteria are highly reliant on microbial culture, which is time consuming (requires > 16 hours), especially at near minimum inhibitory concentration...