John H McNeill
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Explore the profile of John H McNeill including associated specialties, affiliations and a list of published articles.
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80
Citations
1535
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Recent Articles
1.
de Oliveira Garcia F, Sales-Campos H, Yuen V, Machado J, de Barros Viana G, Oliveira C, et al.
Korean J Gastroenterol
. 2020 Sep;
76(3):150-158.
PMID: 32969363
Background/aims: Therapies aimed at modulating cytokines have been used to treat inflammatory illnesses, such as inflammatory bowel disease. On the other hand, patients may become intolerant, refractory, or present with...
2.
Poormasjedi-Meibod M, Mansouri M, Fossey M, Squair J, Liu J, McNeill J, et al.
J Neurotrauma
. 2018 Jun;
36(6):950-961.
PMID: 29877162
Spinal cord injury (SCI) causes autonomic dysfunction, altered neurohumoral control, profound hemodynamic changes, and an increased risk of heart disease. In this prospective study, we investigated the cardiac consequences of...
3.
West C, Squair J, McCracken L, Currie K, Somvanshi R, Yuen V, et al.
Hypertension
. 2016 Oct;
68(5):1281-1289.
PMID: 27698067
Autonomic dysreflexia (AD), which describes episodic hypertension, is highly prevalent in people with spinal cord injury (SCI). In non-SCI, primary hypertension depresses cardiac contractile reserve via β-adrenergic mechanisms. In this...
4.
Vasudevan H, Lau S, Jiang J, McNeill J
J Exp Pharmacol
. 2016 May;
2:169-79.
PMID: 27186103
Testosterone plays an important role in mediating hypertension and altered vascular reactivity associated with insulin resistance. In addition to other pathways, testosterone-dependent changes in aortic cyclooxygenase (COX-2) mRNA levels affect...
5.
Yuen V, Coleman J, Withers S, Andersen R, Brayer G, Mustafa S, et al.
Mol Cell Biochem
. 2015 Nov;
411(1-2):373-81.
PMID: 26547551
Diabetes is an increasingly prevalent disease state with a global impact. It is important that effective and cost-efficient methods be developed to treat this disease state. Zucker diabetic fatty rats,...
6.
Gershkovich P, Wasan K, Ribeyre C, Ibrahim F, McNeill J
Drugs Context
. 2015 Sep;
4:212287.
PMID: 26322116
Purpose: Benzodiazepines (BDZs) are the drugs of choice to prevent the symptoms of alcohol withdrawal syndrome (AWS). Various treatment protocols are published and have been shown to be effective in...
7.
Williams L, Zhang X, Caner S, Tysoe C, Nguyen N, Wicki J, et al.
Nat Chem Biol
. 2015 Jul;
11(9):691-6.
PMID: 26214255
The complex plant flavonol glycoside montbretin A is a potent (Ki = 8 nM) and specific inhibitor of human pancreatic α-amylase with potential as a therapeutic for diabetes and obesity....
8.
Tran L, MacLeod K, McNeill J
Mol Cell Biochem
. 2014 Apr;
392(1-2):205-11.
PMID: 24682694
The purpose of this study was to investigate the effect of chronic treatment with prazosin, a selective α1-adrenoceptor antagonist, on the development of hypertension in fructose-fed rats (FFR). High-fructose feeding...
9.
West C, Crawford M, Poormasjedi-Meibod M, Currie K, Fallavollita A, Yuen V, et al.
J Physiol
. 2014 Feb;
592(8):1771-83.
PMID: 24535438
Spinal cord injury (SCI) causes altered autonomic control and severe physical deconditioning that converge to drive maladaptive cardiac remodelling. We used a clinically relevant experimental model to investigate the cardio-metabolic...
10.
Zhou K, Kumar U, Yuen V, McNeill J
Can J Physiol Pharmacol
. 2012 Jul;
90(8):1075-85.
PMID: 22783820
Metabolic syndrome (MS) is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. MS is associated with obesity, increased blood pressure, hyperlipidemia, and hyperglycemia....