John H Dubinion
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Explore the profile of John H Dubinion including associated specialties, affiliations and a list of published articles.
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8
Citations
196
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Recent Articles
1.
da Silva A, do Carmo J, Dubinion J, Bassi M, Mokhtarpouriani K, Hamza S, et al.
Hypertension
. 2014 Oct;
65(1):171-7.
PMID: 25287400
We examined whether central melanocortin 3 and 4 receptor (MC3/4R) blockade attenuates the blood pressure (BP) responses to chronic L-NAME or angiotensin II (Ang II) infusion in Sprague-Dawley rats implanted...
2.
Dubinion J, do Carmo J, Adi A, Hamza S, da Silva A, Hall J
Hypertension
. 2013 Mar;
61(5):1066-74.
PMID: 23529161
Although signal transducer and activator of transcription 3 (Stat3) is a key second messenger by which leptin regulates appetite and body weight, its role in specific neuronal populations in metabolic...
3.
do Carmo J, da Silva A, Cai Z, Lin S, Dubinion J, Hall J
Hypertension
. 2011 Mar;
57(5):918-26.
PMID: 21422382
Although the central nervous system melanocortin system is an important regulator of energy balance, the role of proopiomelanocortin (POMC) neurons in mediating the chronic effects of leptin on appetite, blood...
4.
Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet
Dubinion J, da Silva A, Hall J
J Hypertens
. 2011 Feb;
29(4):758-62.
PMID: 21311343
Objective: Obesity has been suggested to induce selective leptin resistance whereby leptin's anorexic effects are attenuated, whereas the effects to increase sympathetic nervous system activity and blood pressure remain intact....
5.
Dubinion J, da Silva A, Hall J
J Hypertens
. 2010 May;
28(7):1466-70.
PMID: 20442673
Method: We examined the role of central nervous system (CNS) endogenous melanocortin 3/4 receptors (MC3/4R) activity in controlling cardiovascular and metabolic functions in Sprague Dawley rats fed a high-fat diet...
6.
Jackson E, Dubinion J, Mi Z
Clin Exp Pharmacol Physiol
. 2007 Dec;
35(1):29-34.
PMID: 18047624
1. The aim of the present study was to determine whether inhibition of dipeptidyl peptidase IV (DPP IV) elevates arterial blood pressure and whether any such effect is dependent on...
7.
Dubinion J, Mi Z, Jackson E
J Pharmacol Exp Ther
. 2006 Mar;
317(3):1330-6.
PMID: 16537795
The purpose of this study was to test the hypothesis that renal sympathetic nerves modulate angiotensin II-induced renal vasoconstriction in kidneys from genetically hypertensive rats via Y1 receptors activating the...
8.
Dubinion J, Mi Z, Zhu C, Gao L, Jackson E
Hypertension
. 2005 Dec;
47(3):545-51.
PMID: 16365188
The Gi pathway augments renal vasoconstriction induced by angiotensin II in spontaneously hypertensive but not normotensive Wistar-Kyoto rats. Because the Gi-coupled pancreatic polypeptide (PP)-fold peptide receptors Y1 and Y2 are...