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John Gerhart

Explore the profile of John Gerhart including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 787
Followers 0
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Recent Articles
1.
Andrade Lopez J, Pani A, Wu M, Gerhart J, Lowe C
PLoS Biol . 2023 Sep; 21(9):e3002242. PMID: 37725784
Hemichordates are an important group for investigating the evolution of bilaterian nervous systems. As the closest chordate outgroup with a bilaterally symmetric adult body plan, hemichordates are particularly informative for...
2.
Gerhart J, Pederson T
Science . 2019 Apr; 364(6437):238. PMID: 31000653
No abstract available.
3.
Fritzenwanker J, Uhlinger K, Gerhart J, Silva E, Lowe C
Proc Natl Acad Sci U S A . 2019 Apr; 116(17):8403-8408. PMID: 30967509
The trunk is a key feature of the bilaterian body plan. Despite spectacular morphological diversity in bilaterian trunk anatomies, most insights into trunk development are from segmented taxa, namely arthropods...
4.
Lowe C, Terasaki M, Wu M, Freeman Jr R, Runft L, Kwan K, et al.
PLoS Biol . 2015 Dec; 13(12):e1002354. PMID: 26714185
No abstract available.
5.
Simakov O, Kawashima T, Marletaz F, Jenkins J, Koyanagi R, Mitros T, et al.
Nature . 2015 Nov; 527(7579):459-65. PMID: 26580012
Acorn worms, also known as enteropneust (literally, 'gut-breathing') hemichordates, are marine invertebrates that share features with echinoderms and chordates. Together, these three phyla comprise the deuterostomes. Here we report the...
6.
Lowe C, Clarke D, Medeiros D, Rokhsar D, Gerhart J
Nature . 2015 Apr; 520(7548):456-65. PMID: 25903627
Our understanding of vertebrate origins is powerfully informed by comparative morphology, embryology and genomics of chordates, hemichordates and echinoderms, which together make up the deuterostome clade. Striking body-plan differences among...
7.
Satoh N, Tagawa K, Lowe C, Yu J, Kawashima T, Takahashi H, et al.
Genesis . 2014 Oct; 52(12):925-34. PMID: 25303744
As a group closely related to chordates, hemichordate acorn worms are in a key phylogenic position for addressing hypotheses of chordate origins. The stomochord of acorn worms is an anterior...
8.
Fritzenwanker J, Gerhart J, Freeman Jr R, Lowe C
Evodevo . 2014 Jul; 5:17. PMID: 24987514
Background: The Fox gene family is a large family of transcription factors that arose early in organismal evolution dating back to at least the common ancestor of metazoans and fungi....
9.
Gerhart J
FEBS J . 2013 Aug; 281(2):612-20. PMID: 23953008
Aspartate transcarbamoylase (ATCase) of Escherichia coli, the first enzyme of the pyrimidine biosynthetic pathway, is inhibited by CTP and UTP, the nucleotide end-products of the pathway. First discovered by Yates...
10.
Freeman R, Ikuta T, Wu M, Koyanagi R, Kawashima T, Tagawa K, et al.
Curr Biol . 2012 Oct; 22(21):2053-8. PMID: 23063438
Genomic comparisons of chordates, hemichordates, and echinoderms can inform hypotheses for the evolution of these strikingly different phyla from the last common deuterostome ancestor. Because hox genes play pivotal developmental...