John F Markham
Overview
Explore the profile of John F Markham including associated specialties, affiliations and a list of published articles.
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19
Citations
579
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Recent Articles
1.
Markham J, Fellowes A, Green T, Leal J, Legaie R, Cullerne D, et al.
Br J Cancer
. 2022 Dec;
128(6):1148-1154.
PMID: 36572732
Background: Targeted RNA sequencing (RNA-seq) from FFPE specimens is used clinically in cancer for its ability to estimate gene expression and to detect fusions. Using a cohort of NSCLC patients,...
2.
Thompson E, Nguyen T, Kankanige Y, Markham J, Anderson M, Handunnetti S, et al.
Blood Adv
. 2021 Dec;
6(2):503-508.
PMID: 34861696
The genomic landscape of resistance to targeted agents (TAs) used as monotherapy in chronic lymphocytic leukemia (CLL) is complex and often heterogeneous at the patient level. To gain insight into...
3.
Gould C, Lickiss J, Kankanige Y, Yerneni S, Lade S, Gandhi M, et al.
Br J Haematol
. 2021 Aug;
195(1):113-118.
PMID: 34426978
Richter syndrome (RS), an aggressive lymphoma occurring in the context of chronic lymphocytic leukaemia/small lymphocytic lymphoma, is associated with poor prognosis when treated with conventional immunochemotherapy, therefore, improved treatments are...
4.
Markham J, Yerneni S, Ryland G, Leong H, Fellowes A, Thompson E, et al.
Sci Rep
. 2020 Jun;
10(1):10400.
PMID: 32576910
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Markham J, Yerneni S, Ryland G, Leong H, Fellowes A, Thompson E, et al.
Sci Rep
. 2019 Apr;
9(1):6426.
PMID: 31015508
Next Generation Sequencing is now routinely used in the practice of diagnostic pathology to detect clinically relevant somatic and germline sequence variations in patient samples. However, clinical assessment of copy...
6.
Zhou J, Markham J, Duffy K, Hodgkin P
Front Immunol
. 2018 Sep;
9:2053.
PMID: 30250473
In response to external stimuli, naïve B cells proliferate and take on a range of fates important for immunity. How their fate is determined is a topic of much recent...
7.
Blombery P, Thompson E, Jones K, Arnau G, Lade S, Markham J, et al.
Haematologica
. 2016 May;
101(9):e387-90.
PMID: 27198716
No abstract available.
8.
Kan A, Pavlyshyn D, Markham J, Dowling M, Heinzel S, Zhou J, et al.
PLoS One
. 2016 Jan;
11(1):e0146227.
PMID: 26742110
Adaptive immune responses are complex dynamic processes whereby B and T cells undergo division and differentiation triggered by pathogenic stimuli. Deregulation of the response can lead to severe consequences for...
9.
Budden D, Hurley D, Cursons J, Markham J, Davis M, Crampin E
Epigenetics Chromatin
. 2014 Dec;
7(1):36.
PMID: 25489339
Background: Transcription factors (TFs) and histone modifications (HMs) play critical roles in gene expression by regulating mRNA transcription. Modelling frameworks have been developed to integrate high-throughput omics data, with the...
10.
Potts K, Sargeant T, Markham J, Shi W, Biben C, Josefsson E, et al.
Blood
. 2014 Aug;
124(17):2725-9.
PMID: 25079356
In this study, we test the assumption that the hematopoietic progenitor/colony-forming cells of the embryonic yolk sac (YS), which are endowed with megakaryocytic potential, differentiate into the first platelet-forming cells...