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John Edward Connolly

Explore the profile of John Edward Connolly including associated specialties, affiliations and a list of published articles. Areas
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Citations 157
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Recent Articles
1.
Narmada B, Khakpoor A, Shirgaonkar N, Narayanan S, Aw P, Singh M, et al.
J Hepatol . 2024 Feb; 81(1):42-61. PMID: 38423478
Background & Aims: Hepatitis B surface antigen (HBsAg) loss or functional cure (FC) is considered the optimal therapeutic outcome for patients with chronic hepatitis B (CHB). However, the immune-pathological biomarkers...
2.
Ng H, Lee R, Goh S, Tay I, Lim X, Lee B, et al.
J Immunother Cancer . 2020 Aug; 8(2). PMID: 32847986
Introduction: Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated mortality globally. Immune-checkpoint blockade (ICB) is one of the systemic therapy options for HCC. However, response rates remain low,...
3.
Zharkova O, Tay S, Lee H, Shubhita T, Ong W, Lateef A, et al.
Cytometry A . 2018 Dec; 95(3):268-278. PMID: 30549398
Neutrophil extracellular traps (NETs) are web-like structures composed of decondensed chromatin and antimicrobial proteins that are released into the extracellular space during microbial infections. This active cell death program is...
4.
Sim W, Malinarich F, Fairhurst A, Connolly J
J Vis Exp . 2016 Jul; (112). PMID: 27404554
Immune response results from a complex interplay between the antigen non-specific innate immune system and the antigen specific adaptive immune system. The immune system is a constant balance in maintaining...
5.
Sim W, Ahl P, Connolly J
Mediators Inflamm . 2016 Mar; 2016:2636701. PMID: 26980944
Immunological tolerance is a fundamental tenant of immune homeostasis and overall health. Self-tolerance is a critical component of the immune system that allows for the recognition of self, resulting in...