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John D Sheppard Jr

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Recent Articles
1.
Mason L, Jafri S, Dortonne I, Sheppard Jr J
Expert Opin Emerg Drugs . 2021 Nov; 26(4):401-413. PMID: 34846978
Introduction: Dry Eye Disease (DED) is defined as a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and a vicious cycle of...
2.
Sheppard Jr J, Singh R, McClellan A, Weikert M, Scoper S, Joly T, et al.
Cornea . 2013 Jul; 32(10):1297-304. PMID: 23884332
Purpose: Supplementation with gamma-linolenic acid (GLA) and omega-3 (n-3) polyunsaturated fatty acids (PUFAs) has been found to decrease the production of disease-relevant inflammatory mediators that are implicated in the pathogenesis...
3.
Sheppard Jr J, Nguyen Q, Usner D, Comstock T
Clin Ophthalmol . 2012 Jan; 6:79-85. PMID: 22275811
Purpose: To describe visual acuity (VA) and inflammation following cataract surgery in eyes with noninfectious posterior uveitis (NIPU) that were being treated with a fluocinolone acetonide (FA) intravitreal implant compared...
4.
Hosseini A, Lattanzio Jr F, Samudre S, DiSandro G, Sheppard Jr J, Williams P
J Ocul Pharmacol Ther . 2011 Dec; 28(2):194-201. PMID: 22149555
Purpose: The cornea is one of the most commonly transplanted tissues. The morpholino-oligomer antisense compound AVI-5126 suppresses expression of proto-oncogene c-myc, a key factor in transplant rejection. AVI-5126 was evaluated...
5.
Samudre S, Lattanzio Jr F, Lossen V, Hosseini A, Sheppard Jr J, McKown R, et al.
Invest Ophthalmol Vis Sci . 2010 Nov; 52(9):6265-70. PMID: 21087963
Purpose: Lacritin is a novel human tear glycoprotein that promotes basal tear peroxidase secretion by rat lacrimal acinar cells in vitro. This study investigates whether lacritin is prosecretory when added...
6.
Samudre S, Schneider J, Oltmanns M, Hosseini A, Pratap K, Loose-Thurman P, et al.
Curr Eye Res . 2008 Oct; 33(10):857-63. PMID: 18853319
Objective: This study compares the effect of topical versus intravenous (IV) administration of synthetic WIN 55-212-2 (WIN) or timolol on intraocular pressure (IOP). Methods: WIN or timolol were administered either...
7.
Asbell P, Colby K, Deng S, McDonnell P, Meisler D, Raizman M, et al.
Am J Ophthalmol . 2008 Apr; 145(6):951-958. PMID: 18374299
Purpose: Ocular Tracking Resistance in U.S. Today (TRUST) annually evaluates in vitro antimicrobial susceptibility of Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae to ciprofloxacin, gatifloxacin, levofloxacin, moxifloxacin, penicillin, azithromycin, tobramycin,...
8.
Sheppard Jr J, Epstein R, Lattanzio Jr F, Marcantonio D, Williams P
Am J Ophthalmol . 2006 Feb; 141(3):524-529. PMID: 16490500
Purpose: Long-term evaluation of dihematoporphyrin ether (DHE) safety and efficacy as photodynamic therapy (PDT) for patients with corneal neovascularization (KNV). Design: Prospective multi-center interventional case series. Methods: Seven patients were...
9.
Williams P, Sheppard Jr J
Expert Opin Biol Ther . 2005 Dec; 5(12):1603-9. PMID: 16318424
Conjunctival and corneal manifestations of atopic keratoconjunctivitis (AKC) are chronic, disabling and may be blinding. In common with other allergic diseases, such as asthma and atopic dermatitis, AKC is characterised...
10.
Sheppard Jr J, Lattanzio Jr F, Williams P, Mitrev P, Allen R
Cornea . 2005 Feb; 24(2):227-9. PMID: 15725894
Purpose: To report the early, rapid diagnosis of the Chandler variant of the iridocorneal endothelial (ICE) syndrome using confocal light microscopy. Methods: A 62-year-old man with a long history of...