John D Alvarez
Overview
Explore the profile of John D Alvarez including associated specialties, affiliations and a list of published articles.
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5
Citations
125
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0
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Recent Articles
1.
Bruscaggin A, di Bergamo L, Spina V, Hodkinson B, Forestieri G, Bonfiglio F, et al.
Blood Adv
. 2021 Sep;
5(22):4674-4685.
PMID: 34500472
To advance the use of circulating tumor DNA (ctDNA) applications, their broad clinical validity must be tested in different treatment settings, including targeted therapies. Using the prespecified longitudinal systematic collection...
2.
Karkera J, Cardona G, Bell K, Gaffney D, Portale J, Santiago-Walker A, et al.
Mol Cancer Ther
. 2017 Apr;
16(8):1717-1726.
PMID: 28416604
Fibroblast growth factor receptor (FGFR) genetic alterations are frequently observed in cancer, suggesting that FGFR inhibition may be a promising therapy in patients harboring these lesions. Identification of predictive and...
3.
Casneuf T, Axel A, King P, Alvarez J, Werbeck J, Verhulst T, et al.
Breast Cancer (Dove Med Press)
. 2016 Feb;
8:13-27.
PMID: 26893580
Introduction: Interleukin-6 (IL-6) is an important growth factor for estrogen receptor-α (ERα)-positive breast cancer, and elevated serum IL-6 is associated with poor prognosis. Methods: The role of the phosphorylated signal...
4.
Sellar G, Alvarez J, Loganzo F, Abbas R, Immermann F, Karnoub M, et al.
Biomark Med
. 2010 May;
2(2):147-53.
PMID: 20477436
An area of unmet medical need in clinical oncology has been optimizing patient selection for a given therapeutic with the goal of getting the right drug to the right patient....
5.
Zheng X, Yang Z, Yue Z, Alvarez J, Sehgal A
Proc Natl Acad Sci U S A
. 2007 Sep;
104(40):15899-904.
PMID: 17895391
Circadian rhythms can be regulated by many environmental and endogenous factors. We show here a sensitivity of circadian clock function to oxidative stress that is revealed in flies lacking the...