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John C Schwartz

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Articles 31
Citations 867
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Recent Articles
1.
Schwartz J, Farrell C, Freimanis G, Sewell A, Phillips J, Hammond J
Immunogenetics . 2024 Sep; 76(5-6):361-380. PMID: 39294478
The inbred Babraham pig serves as a valuable biomedical model for research due to its high level of homozygosity, including in the major histocompatibility complex (MHC) loci and likely other...
2.
Noble A, Paudyal B, Schwartz J, Mwangi W, Munir D, Tchilian E, et al.
Front Immunol . 2023 Dec; 14:1286903. PMID: 38077405
Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not fully described for bovine IgG1, 2 and 3....
3.
Ramirez Valdez K, Nzau B, Dorey-Robinson D, Jarman M, Nyagwange J, Schwartz J, et al.
Vaccines (Basel) . 2023 Jun; 11(6). PMID: 37376488
Studying the antibody response to infection or vaccination is essential for developing more effective vaccines and therapeutics. Advances in high-throughput antibody sequencing technologies and immunoinformatic tools now allow the fast...
4.
Paudyal B, Mwangi W, Rijal P, Schwartz J, Noble A, Shaw A, et al.
Front Immunol . 2022 Jun; 13:903755. PMID: 35757698
The pig is an important agricultural species and powerful biomedical model. We have established the pig, a large natural host animal for influenza with many physiological similarities to humans, as...
5.
Schwartz J, Maccari G, Heimeier D, Hammond J
HLA . 2021 Nov; 99(3):167-182. PMID: 34802191
The major histocompatibility complex (MHC) class I region of cattle is both highly polymorphic and, unlike many species, highly variable in gene content between haplotypes. Cattle MHC class I alleles...
6.
Holzer B, Rijal P, McNee A, Paudyal B, Martini V, Clark B, et al.
PLoS Pathog . 2021 Aug; 17(8):e1009815. PMID: 34347851
[This corrects the article DOI: 10.1371/journal.ppat.1009330.].
7.
Le Page L, Gillespie A, Schwartz J, Prawits L, Schlerka A, Farrell C, et al.
Dev Comp Immunol . 2021 Jul; 125:104214. PMID: 34329647
γδ T cells constitute a major portion of lymphocytes in the blood of both ruminants and swine. Subpopulations of swine γδ T cells have been distinguished by CD2 and CD8α...
8.
Genena K, Ahmed S, Szerlip H, Schwartz J
Hemodial Int . 2021 Jun; 25(4):424-432. PMID: 34145961
The dialysis disequilibrium syndrome (DDS) results from osmotic shifts between the blood and the brain compartments. Patients at risk for DDS include those with very elevated blood urea nitrogen, concomitant...
9.
Holzer B, Rijal P, McNee A, Paudyal B, Martini V, Clark B, et al.
PLoS Pathog . 2021 Mar; 17(3):e1009330. PMID: 33662023
Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies transmissions in both directions. The emergence of...
10.
Rosen B, Bickhart D, Schnabel R, Koren S, Elsik C, Tseng E, et al.
Gigascience . 2020 Mar; 9(3). PMID: 32191811
Background: Major advances in selection progress for cattle have been made following the introduction of genomic tools over the past 10-12 years. These tools depend upon the Bos taurus reference...