John C S Harding
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Explore the profile of John C S Harding including associated specialties, affiliations and a list of published articles.
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95
Citations
822
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Recent Articles
1.
Steinerova K, Harding J, Parker S, Wilson H, Finatto A, Seddon Y
Front Vet Sci
. 2024 Oct;
11:1460993.
PMID: 39355142
Positive emotions can reduce disease susceptibility during infectious challenges in humans, and emerging evidence suggests similar effects in farm animals. Because play behaviour may support a positive emotional state in...
2.
Challa N, Enns C, Keith B, Harding J, Loewen M
Am J Physiol Gastrointest Liver Physiol
. 2024 Aug;
327(5):G655-G672.
PMID: 39104321
In this study, we uncovered the novel mechanism of IL-1α-mediated downregulated in adenoma (DRA) () downregulation in the context of spp.induced malabsorptive diarrhea. Experimentally infected pigs with spp. had significantly...
3.
Ko H, Pasternak J, Mulligan M, Hamonic G, Ramesh N, MacPhee D, et al.
BMC Vet Res
. 2024 Jun;
20(1):255.
PMID: 38867209
Background: Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) infection during late gestation substantially lowers fetal viability and survival. In a previous genome-wide association study, a single nucleotide polymorphism on...
4.
Barbosa J, Aguirre J, Nosach R, Harding J, Cantarelli V, Costa M
PLoS One
. 2023 Nov;
18(11):e0294273.
PMID: 37948383
Swine dysentery (SD) is a worldwide production-limiting disease of growing-finishing pigs in commercial farms. The importance of the large intestinal microbiota in the swine dysentery pathogenesis has been established, but...
5.
Kulathunga D, Harding J, Rubin J
PLoS One
. 2023 Jun;
18(6):e0286594.
PMID: 37390052
The re-emergence of Brachyspira-associated disease in pigs since the late 2000s has illuminated some of the diagnostic challenges associated with this genus; notably, the lack of standardized antimicrobial susceptibility testing...
6.
Parra-Aguirre J, Nosach R, Fernando C, Hill J, Harding J
Vet Res
. 2023 Jun;
54(1):49.
PMID: 37328906
Swine dysentery (SD) caused by pathogenic Brachyspira spp. is an economic challenge for the swine industry. In research settings, experimental reproduction of swine dysentery typically relies on intragastric inoculation which...
7.
Van Goor A, Pasternak A, Walugembe M, Chehab N, Hamonic G, Dekkers J, et al.
Front Genet
. 2023 Feb;
14:1110463.
PMID: 36845393
Porcine reproductive and respiratory syndrome virus (PRRSV) causes respiratory disease in piglets and reproductive disease in sows. Piglet and fetal serum thyroid hormone (i.e., T3 and T4) levels decrease rapidly...
8.
Dervishi E, Bai X, Cheng J, Fortin F, Dyck M, Harding J, et al.
J Anim Sci
. 2023 Jan;
101.
PMID: 36705540
The purpose of this study was to explore plasma metabolite levels in young healthy pigs and their potential association with disease resilience and estimate genetic and phenotypic correlation with the...
9.
Chen Y, Lonergan S, Lim K, Cheng J, Putz A, Dyck M, et al.
J Anim Sci
. 2023 Jan;
101.
PMID: 36638126
Selection for disease resilience, which refers to the ability of an animal to maintain performance when exposed to disease, can reduce the impact of infectious diseases. However, direct selection for...
10.
Ison E, Hopf-Jannasch A, Harding J, Pasternak J
Vet Res
. 2022 Sep;
53(1):74.
PMID: 36175938
Porcine reproductive and respiratory syndrome virus (PRRSV) in late gestation causes a profound suppression of circulating maternal and fetal thyroid hormone during a critical window of development. To understand this...