John C Bischof
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Explore the profile of John C Bischof including associated specialties, affiliations and a list of published articles.
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134
Citations
2673
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Recent Articles
1.
Kangas J, Hogan Jr C, Bischof J
Cryobiology
. 2025 Jan;
118:105198.
PMID: 39824240
Osmotic stresses during cryoprotectant loading induce changes in cellular volume, leading to membrane damage or even cell death. Appropriate model-guided mitigation of these osmotic gradients during cryoprotectant loading is currently...
2.
Ramesh S, Rao J, Namsrai B, Fisher B, Tobolt D, Megaly M, et al.
bioRxiv
. 2024 Dec;
PMID: 39713303
Background And Aims: High-throughput in vitro pharmacological toxicity testing is essential for drug discovery. Precision-cut liver slices (PCLS) provide a robust system for screening that is more representative of the...
3.
Gangwar L, Han Z, Scheithauer C, Namsrai B, Kantesaria S, Goldstein R, et al.
bioRxiv
. 2024 Nov;
PMID: 39605575
Organ banking by vitrification could revolutionize transplant medicine. However, vitrification and rewarming have never been demonstrated at the human organ scale. Using modeling and experimentation, we tested the ability to...
4.
Han Z, Gangwar L, Namsrai B, Rao J, Scheithauer C, Etheridge M, et al.
Cryobiology
. 2024 Oct;
117:104977.
PMID: 39368531
Critical cooling and warming rates (CCR and CWR) are two important calorimetric properties of cryoprotective agents (CPA) solutions, and achieving these rates is generally regarded as the critical criterion for...
5.
Pruett T, Wolf S, McVan C, Lyon P, Capron A, Childress J, et al.
Am J Transplant
. 2024 Sep;
25(2):269-276.
PMID: 39306279
Time limits on organ viability from retrieval to implantation shape the US system for human organ transplantation. Preclinical research has demonstrated that emerging biopreservation technologies can prolong organ viability, perhaps...
6.
Liu S, Han Z, Ye Z, Jiang M, Etheridge M, Bischof J, et al.
Nano Lett
. 2024 Sep;
24(37):11567-11572.
PMID: 39230046
Rewarming cryopreserved samples requires fast heating to avoid devitrification, a challenge previously attempted by magnetic nanoparticle-mediated hyperthermia. Here, we introduce FeO@SiO nanorods as the heating elements to manipulate the heating...
7.
Hagedorn M, Parenti L, Craddock R, Comizzoli P, Mabee P, Meinke B, et al.
Bioscience
. 2024 Sep;
74(8):561-566.
PMID: 39229623
Earth's biodiversity is increasingly threatened and at risk. We propose a passive lunar biorepository for long-term storage of prioritized taxa of live cryopreserved samples to safeguard Earth's biodiversity and to...
8.
Han G, Khosla K, Smith K, Ng D, Lee J, Ouyang X, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(32):e2404617.
PMID: 39031674
Devising an approach to deterministically position organisms can impact various fields such as bioimaging, cybernetics, cryopreservation, and organism-integrated devices. This requires continuously assessing the locations of randomly distributed organisms to...
9.
Ozgur O, Namsrai B, Pruett T, Bischof J, Toner M, Finger E, et al.
Front Transplant
. 2024 Jul;
2:1156845.
PMID: 38993842
Organ transplantation remains the only treatment option for patients with end-stage organ failure. The last decade has seen a flurry of activity in improving organ preservation technologies, which promise to...
10.
Ye Z, Tai Y, Han Z, Liu S, Etheridge M, Pasek-Allen J, et al.
Nano Lett
. 2024 Apr;
24(15):4588-4594.
PMID: 38587406
Effective thawing of cryopreserved samples requires rapid and uniform heating. This is achievable through nanowarming, an approach that heats magnetic nanoparticles by using alternating magnetic fields. Here we demonstrate the...