Johannes Virtanen
Overview
Explore the profile of Johannes Virtanen including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
297
Followers
0
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Recent Articles
1.
de Vera C, Diaz Crespin G, Hernandez Daranas A, Montalvao Looga S, Lillsunde K, Tammela P, et al.
Mar Drugs
. 2018 Sep;
16(9).
PMID: 30200664
The study of marine natural products for their bioactive potential has gained strength in recent years. Oceans harbor a vast variety of organisms that offer a biological and chemical diversity...
2.
Akerfelt M, Bayramoglu N, Robinson S, Toriseva M, Schukov H, Harma V, et al.
Oncotarget
. 2015 Sep;
6(30):30035-56.
PMID: 26375443
Cancer-associated fibroblasts (CAFs) constitute an important part of the tumor microenvironment and promote invasion via paracrine functions and physical impact on the tumor. Although the importance of including CAFs into...
3.
Harma V, Haavikko R, Virtanen J, Ahonen I, Schukov H, Alakurtti S, et al.
PLoS One
. 2015 May;
10(5):e0126111.
PMID: 25965345
The anti-invasive and anti-proliferative effects of betulins and abietane derivatives was systematically tested using an organotypic model system of advanced, castration-resistant prostate cancers. A preliminary screen of the initial set...
4.
Harma V, Schukov H, Happonen A, Ahonen I, Virtanen J, Siitari H, et al.
PLoS One
. 2014 May;
9(5):e96426.
PMID: 24810913
Glandular epithelial cells differentiate into complex multicellular or acinar structures, when embedded in three-dimensional (3D) extracellular matrix. The spectrum of different multicellular morphologies formed in 3D is a sensitive indicator...
5.
Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppanen-Laakso T, Virtanen J, et al.
Oncotarget
. 2011 Dec;
2(12):1176-90.
PMID: 22202492
Prostate cancer is the second leading cause of cancer mortality in men in developed countries. Due to the heterogeneous nature of the disease, design of novel personalized treatments is required...
6.
Harma V, Virtanen J, Makela R, Happonen A, Mpindi J, Knuuttila M, et al.
PLoS One
. 2010 May;
5(5):e10431.
PMID: 20454659
Prostate epithelial cells from both normal and cancer tissues, grown in three-dimensional (3D) culture as spheroids, represent promising in vitro models for the study of normal and cancer-relevant patterns of...