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Johannes Krug

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Articles 16
Citations 40
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Recent Articles
1.
Lin M, Sihota P, Kolibova S, Fiedler I, Krug J, Wolfel E, et al.
JBMR Plus . 2025 Jan; 9(2):ziae151. PMID: 39822214
Advanced glycation end products (AGEs) accumulate in various tissues, including bone, due to aging and conditions like diabetes mellitus. To investigate the effects of AGEs on bone material quality and...
2.
Krug J, Plumeyer C, Davydok A, Kolibova S, Fischer N, Le-Phuoc X, et al.
Biomater Adv . 2024 Nov; 167:214060. PMID: 39486241
Bone metastases related to breast and prostate cancer present with multiple challenges and skeletal related events like fragility fractures impair the quality of life of the patients significantly. To determine...
3.
Faraj M, Leanza G, Krug J, Cannata F, Viola V, Zampogna B, et al.
JBMR Plus . 2024 Sep; 8(10):ziae111. PMID: 39253598
Bone fragility is a recognized complication of type 2 diabetes mellitus (T2DM), increasing patient morbidity. Thus, the development of an effective intervention to prevent diabetic bone fragility is urgently needed....
4.
Vom Scheidt A, Krug J, Goggin P, Bakker A, Busse B
Curr Osteoporos Rep . 2024 Jul; 22(4):396-415. PMID: 38980532
Purpose Of Review: Quantification of the morphology of osteocyte lacunae has become a powerful tool to investigate bone metabolism, pathologies and aging. This review will provide a brief overview of...
5.
Wolfel E, Bartsch B, Koldehoff J, Fiedler I, Dragoun-Kolibova S, Schmidt F, et al.
JBMR Plus . 2023 Dec; 7(12):e10839. PMID: 38130774
Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting bone tissue and leading to increased fracture risk in men and women, independent of bone mineral density (BMD). Thus, bone...
6.
Emini L, Salbach-Hirsch J, Krug J, Jahn-Rickert K, Busse B, Rauner M, et al.
JBMR Plus . 2023 Dec; 7(12):e10843. PMID: 38130754
Type 2 diabetes mellitus (T2DM) increases risk of fractures due to bone microstructural and material deficits, though the mechanisms remain unclear. Preclinical models mimicking diabetic bone disease are required to...
7.
Ruparelia A, Salavaty A, Barlow C, Lu Y, Sonntag C, Hersey L, et al.
Aging Cell . 2023 May; 23(1):e13862. PMID: 37183563
Sarcopenia, the age-related decline in muscle function, places a considerable burden on health-care systems. While the stereotypic hallmarks of sarcopenia are well characterized, their contribution to muscle wasting remains elusive,...
8.
Krug J, Richter A, Englert C
Cold Spring Harb Protoc . 2023 Feb; 2023(8):107744. PMID: 36828577
CRISPR-Cas9 has eased the induction of sequence-specific mutations and has therefore become a powerful tool to generate mutant lines for studying the role of specific genes. The cellular repair of...
9.
Krug J, Perner B, Albertz C, Morl H, Hopfenmuller V, Englert C
Elife . 2023 Feb; 12. PMID: 36820520
Body pigmentation is a limitation for imaging and thus for the performance of longitudinal studies in biomedicine. A possibility to circumvent this obstacle is the employment of pigmentation mutants, which...
10.
Richter A, Krug J, Englert C
Cold Spring Harb Protoc . 2022 Sep; 2022(12):630-640. PMID: 36167675
Differences between the sexes are of increasing interest in basic and applied research with regard to development, behavior, aging, and diseases. Although the African turquoise killifish , a model for...