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Johannes F M G Aerts

Explore the profile of Johannes F M G Aerts including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Fog C, Zago P, Malini E, Solanko L, Peruzzo P, Bornaes C, et al.
EBioMedicine . 2018 Dec; 38:142-153. PMID: 30497978
Background: Gaucher Disease is caused by mutations of the GBA gene which encodes the lysosomal enzyme acid beta-glucosidase (GCase). GBA mutations commonly affect GCase function by perturbing its protein homeostasis...
2.
Elstein D, Dweck A, Attias D, Hadas-Halpern I, Zevin S, Altarescu G, et al.
Blood . 2007 Jul; 110(7):2296-301. PMID: 17609429
Enzyme replacement therapy (ERT) with imiglucerase reduces hepatosplenomegaly and improves hematologic parameters in Gaucher disease type 1 within 6-24 months. Miglustat reduces organomegaly, improves hematologic parameters, and reverses bone marrow...
3.
Maas M, van Kuijk C, Stoker J, Hollak C, Akkerman E, Aerts J, et al.
Radiology . 2003 Oct; 229(2):554-61. PMID: 14526090
Purpose: To develop a semiquantitative magnetic resonance (MR) imaging bone marrow burden (BMB) score with inclusion of both axial and peripheral bone marrow in Gaucher disease as an alternative to...