Johannes Dodt
Overview
Explore the profile of Johannes Dodt including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
111
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Recent Articles
1.
Singh S, Pezeshkpoor B, Jamil M, Dodt J, Sharma A, Ramar V, et al.
J Thromb Haemost
. 2023 Oct;
22(2):379-393.
PMID: 37832789
Background: The characterization of inherited mild factor XIII deficiency is more imprecise than its rare, inherited severe forms. It is known that heterozygosity at FXIII genetic loci results in mild...
2.
Ovanesov M, Williams S, Nubling C, Dodt J, Hilger A, Maryuningsih Y, et al.
Biologicals
. 2020 Aug;
67:88-93.
PMID: 32847723
In recent years, several modified recombinant factor (F) VIII and FIX therapeutics with extended half-life have been licensed internationally for the treatment of haemophilia. Safe and effective use of these...
3.
Singh S, Dodt J, Volkers P, Hethershaw E, Philippou H, Ivaskevicius V, et al.
Sci Rep
. 2019 Aug;
9(1):11324.
PMID: 31383913
The dimeric FXIII-A, a pro-transglutaminase is the catalytic part of the heterotetrameric coagulation FXIII-AB complex that upon activation by calcium binding/thrombin cleavage covalently cross-links preformed fibrin clots protecting them from...
4.
Singh S, Akhter M, Dodt J, Volkers P, Reuter A, Reinhart C, et al.
Int J Mol Sci
. 2019 Jun;
20(11).
PMID: 31159152
Coagulation factor XIII (FXIII) is a plasma-circulating heterotetrameric pro-transglutaminase complex that is composed of two catalytic FXIII-A and two protective/regulatory FXIII-B subunits. FXIII acts by forming covalent cross-links within a...
5.
Singh S, Akhter M, Dodt J, Sharma A, Kaniyappan S, Yadegari H, et al.
Int J Mol Sci
. 2019 Apr;
20(8).
PMID: 31013569
Congenital FXIII deficiency is a rare bleeding disorder in which mutations are detected in and genes that express the two subunits of coagulation FXIII, the catalytic FXIII-A, and protective FXIII-B....
6.
Gupta S, Biswas A, Akhter M, Krettler C, Reinhart C, Dodt J, et al.
Sci Rep
. 2016 Jul;
6:30105.
PMID: 27453290
The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of...
7.
Thomas A, Biswas A, Dodt J, Philippou H, Hethershaw E, Ensikat H, et al.
Hum Mutat
. 2016 Jul;
37(10):1030-41.
PMID: 27363989
Inherited defects of coagulation Factor XIII (FXIII) can be categorized into severe and mild forms based on their genotype and phenotype. Heterozygous mutations occurring in F13A1 and F13B genes causing...
8.
Dodt J, Pasternack R, Seitz R, Volkers P
Br J Haematol
. 2015 Oct;
172(3):452-60.
PMID: 26516704
In a factor XIIIa (FXIIIa) generation assay with recombinant FXIII-A2 (rFXIII-A2 ) free FXIII activation peptide (fAP-FXII) prolonged the time to peak (TTP) but did not affect the area under...
9.
Schroeder V, Handrkova H, Dodt J, Kohler H
Br J Haematol
. 2014 Oct;
168(5):757-9.
PMID: 25284283
No abstract available.
10.
Dodt J, Volkers P, Seitz R
Anal Biochem
. 2013 Apr;
439(2):145-51.
PMID: 23611748
Triggering the extrinsic coagulation pathway in plasma and using a fluorogenic factor XIIIa (FXIIIa) substrate for continuously monitoring FXIIIa activity, an FXIIIa generation curve is obtained. The parameters area under...