Johannes C Schittny
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Explore the profile of Johannes C Schittny including associated specialties, affiliations and a list of published articles.
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41
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959
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Recent Articles
1.
Blaskovic S, Anagnostopoulou P, Borisova E, Schittny D, Donati Y, Haberthur D, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830589
(1) Background: Stereological estimations significantly contributed to our understanding of lung anatomy and physiology. Taking stereology fully 3-dimensional facilitates the estimation of novel parameters. (2) Methods: We developed a protocol...
2.
Islam A, Ronco A, Becker S, Blackburn J, Schittny J, Kim K, et al.
Anat Rec (Hoboken)
. 2023 Sep;
307(2):457-469.
PMID: 37771211
The goal of this study is to assess the feasibility of airway geometry as a biomarker for autism spectrum disorder (ASD). Chest computed tomography images of children with a documented...
3.
Schmid L, Hyde D, Schittny J
Am J Physiol Lung Cell Mol Physiol
. 2023 Aug;
325(5):L537-L541.
PMID: 37605833
Primary and secondary septa formed during lung development contain a double-layered capillary network. To improve gas exchange, the capillary network is remodeled into a single-layered one, a process that is...
4.
Gremlich S, Cremona T, Yao E, Chabenet F, Fytianos K, Roth-Kleiner M, et al.
Front Physiol
. 2021 Nov;
12:749776.
PMID: 34777012
Lung aging is characterized by lung function impairment, ECM remodeling and airspace enlargement. Tenascin-C (TNC) is a large extracellular matrix (ECM) protein with paracrine and autocrine regulatory functions on cell...
5.
Haberthur D, Yao E, Barre S, Cremona T, Tschanz S, Schittny J
PLoS One
. 2021 Nov;
16(11):e0257349.
PMID: 34748555
Pulmonary acini represent the functional gas-exchanging units of the lung. Due to technical limitations, individual acini cannot be identified on microscopic lung sections. To overcome these limitations, we imaged the...
6.
Cremona T, Hartner A, Schittny J
Front Physiol
. 2021 Jan;
11:530635.
PMID: 33408636
Lung development involves epithelial-mesenchymal interactions and integrins represent one of the key elements. These extracellular matrix receptors form hetero-dimers of alpha and beta subunits. The integrin α8β1 is highly expressed...
7.
Sutter M, Cremona T, Nita I, Cavarra E, Lungarella G, Lewis E, et al.
Pharmaceutics
. 2020 Aug;
12(9).
PMID: 32825773
Rationale: Mutation in the alpha1 antitrypsin (AAT) gene leads to low circulating levels of AAT, which is associated with several disease processes including pulmonary emphysema. The standard of care relies...
8.
Gremlich S, Roth-Kleiner M, Equey L, Fytianos K, Schittny J, Cremona T
Sci Rep
. 2020 Mar;
10(1):5118.
PMID: 32198404
Tenascin-C (TNC) is an extracellular matrix protein expressed at high levels during lung organogenesis. Later, TNC is only transiently de novo expressed to orchestrate tissue repair in pathological situations. We...
9.
Borisova E, Lovric G, Miettinen A, Fardin L, Bayat S, Larsson A, et al.
Histochem Cell Biol
. 2020 Mar;
155(2):215-226.
PMID: 32189111
In this article, we present an X-ray tomographic imaging method that is well suited for pulmonary disease studies in animal models to resolve the full pathway from gas intake to...
10.
Mund S, Schittny J
J Appl Physiol (1985)
. 2020 Feb;
128(5):1287-1298.
PMID: 32078464
After the airways have been formed by branching morphogenesis the gas exchange area of the developing lung is enlarged by the formation of new alveolar septa (alveolarization). The septa themselves...