Johannes Beckers
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Explore the profile of Johannes Beckers including associated specialties, affiliations and a list of published articles.
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Articles
186
Citations
7580
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Recent Articles
1.
Stoleriu M, Ansari M, Strunz M, Schamberger A, Heydarian M, Ding Y, et al.
Thorax
. 2024 Jan;
79(6):524-537.
PMID: 38286613
Introduction: Environmental pollutants injure the mucociliary elevator, thereby provoking disease progression in chronic obstructive pulmonary disease (COPD). Epithelial resilience mechanisms to environmental nanoparticles in health and disease are poorly characterised....
2.
Upadhyay S, Rahman M, Rinaldi S, Koelmel J, Lin E, Mahesh P, et al.
Respir Res
. 2024 Jan;
25(1):49.
PMID: 38245732
Background: Chronic obstructive pulmonary disease (COPD) has the highest increased risk due to household air pollution arising from biomass fuel burning. However, knowledge on COPD patho-mechanisms is mainly limited to...
3.
Mayr C, Sengupta A, Asgharpour S, Ansari M, Pestoni J, Ogar P, et al.
Eur Respir J
. 2024 Jan;
63(2).
PMID: 38212077
Background: Fibroblast-to-myofibroblast conversion is a major driver of tissue remodelling in organ fibrosis. Distinct lineages of fibroblasts support homeostatic tissue niche functions, yet their specific activation states and phenotypic trajectories...
4.
Sabikunnahar B, Caldwell S, Varnum S, Hogan T, Lahue K, Rathkolb B, et al.
Physiol Rep
. 2024 Jan;
12(1):e15901.
PMID: 38171546
Obesity is a global health problem characterized by excessive fat accumulation, driven by adipogenesis and lipid accumulation. Long non-coding RNAs (lncRNAs) have recently been implicated in regulating adipogenesis and adipose...
5.
Kovac L, Goj T, Ouni M, Irmler M, Jahnert M, Beckers J, et al.
J Clin Endocrinol Metab
. 2023 Nov;
109(5):1318-1327.
PMID: 37988600
Context: Exercise training is known to improve glucose tolerance and reverse insulin resistance in people with obesity. However, some individuals fail to improve or even decline in their clinical traits...
6.
Han L, Haefner V, Yu Y, Han B, Ren H, Irmler M, et al.
ACS Nano
. 2023 Oct;
17(21):21056-21072.
PMID: 37856828
Nanoparticles (NPs) released from engineered materials or combustion processes as well as persistent herpesvirus infection are omnipresent and are associated with chronic lung diseases. Previously, we showed that pulmonary exposure...
7.
Maurer J, Zhao X, Irmler M, Gudiksen A, Pilmark N, Li Q, et al.
Am J Physiol Cell Physiol
. 2023 Sep;
325(4):C1131-C1143.
PMID: 37694284
Metformin-induced glycolysis and lactate production can lead to acidosis as a life-threatening side effect, but slight increases in blood lactate levels in a physiological range were also reported in metformin-treated...
8.
Ouni M, Eichelmann F, Jahnert M, Krause C, Saussenthaler S, Ott C, et al.
Mol Metab
. 2023 Jul;
75:101774.
PMID: 37429525
Objectives: Better disease management can be achieved with earlier detection through robust, sensitive, and easily accessible biomarkers. The aim of the current study was to identify novel epigenetic biomarkers determining...
9.
Lucienne M, Gerlini R, Rathkolb B, Calzada-Wack J, Forny P, Wueest S, et al.
Hum Mol Genet
. 2023 Jun;
32(17):2717-2734.
PMID: 37369025
Inherited disorders of mitochondrial metabolism, including isolated methylmalonic aciduria, present unique challenges to energetic homeostasis by disrupting energy-producing pathways. To better understand global responses to energy shortage, we investigated a...
10.
Dreher S, Irmler M, Pivovarova-Ramich O, Kessler K, Jurchott K, Sticht C, et al.
Int J Obes (Lond)
. 2023 Feb;
47(4):313-324.
PMID: 36774413
Background: Exercise exerts many health benefits by directly inducing molecular alterations in physically utilized skeletal muscle. Molecular adaptations of subcutaneous adipose tissue (SCAT) might also contribute to the prevention of...