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Johan Smitz

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Articles 143
Citations 2193
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Recent Articles
1.
Smitz J, Sanchez F, Romero S, Van Ranst H, Anckaert E, Gilchrist R, et al.
Reprod Med Biol . 2025 Mar; 24(1):e12640. PMID: 40078334
Background: In vitro oocyte maturation (IVM) is not a novel concept; however, its wide-scale practice has been limited because of the lower clinical outcomes compared to conventional assisted reproductive technologies....
2.
Cava-Cami B, Galvao A, Van Ranst H, Stocker W, Harrison C, Smitz J, et al.
Mol Hum Reprod . 2025 Jan; 31(1). PMID: 39862403
Biphasic IVM can be offered as a patient-friendly alternative to conventional ovarian stimulation in IVF patients predicted to be hyper-responsive to ovarian stimulation. However, cumulative live birth rates after IVM...
3.
Pham H, Le A, Nguyen T, Ma M, Akin N, Pham T, et al.
Reprod Med Biol . 2024 Jun; 23(1):e12587. PMID: 38854775
Purpose: This study investigated the differences in the maturation rate of single versus grouped cumulus-oocyte complexes (COCs) culture methods for capacitation in vitro maturation (CAPA-IVM) in women with polycystic ovary...
4.
Adriaenssens T, Van Vaerenbergh I, Van Landuyt L, Verheyen G, De Brucker M, Camus M, et al.
PLoS One . 2024 Jan; 19(1):e0297040. PMID: 38295095
Research Question: Can a strategy for scoring oocyte quality, based on cumulus cell (CC) gene expression, prioritize oocytes with the highest implantation potential, while limiting the number of embryos to...
5.
Saucedo-Cuevas L, Ma M, Le A, Akin N, Pham T, Ho T, et al.
Fertil Steril . 2023 Dec; 121(3):506-518. PMID: 38052376
Objective: To investigate alterations of the global DNA methylation profile in placenta, cord blood, and neonatal buccal smears in infants conceived using in vitro maturation (IVM) with a prematuration step...
6.
Herta A, Akin N, Segers I, Billooye K, Smitz J, Anckaert E
Reproduction . 2023 Oct; 166(6):369-381. PMID: 37855411
In Brief: Partially denuded mouse cumulus-oocyte complexes restore likely functional transzonal projections in culture, under meiotic inhibition, with no detectable impact on oocyte competence. This proof-of-concept study constitutes positive premises...
7.
Herta A, von Mengden L, Akin N, Billooye K, Coucke W, Cava-Cami B, et al.
J Assist Reprod Genet . 2023 Sep; 40(12):2851-2863. PMID: 37776437
Purpose: Glucose and redox metabolism characterization in mouse antral follicles with meiotically blocked oocytes, after in vitro follicle culture (IFC) from the early secondary stage. Methods: Following IFC (10 days),...
8.
Gilchrist R, Ho T, De Vos M, Sanchez F, Romero S, Ledger W, et al.
Hum Reprod Update . 2023 Aug; 30(1):3-25. PMID: 37639630
Background: While oocyte IVM is practiced sporadically it has not achieved widespread clinical practice globally. However, recently there have been some seminal advances in our understanding of basic aspects of...
9.
Akin N, Ates G, von Mengden L, Herta A, Meriggioli C, Billooye K, et al.
Biol Reprod . 2023 Aug; 109(4):432-449. PMID: 37531262
In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced hormone-related side effects and treatment burden compared to conventional IVF. Capacitation (CAPA)-IVM is a bi-phasic IVM system with...
10.
Gilchrist R, Smitz J
Fertil Steril . 2023 Feb; 119(4):524-539. PMID: 36804961
Oocyte in vitro maturation (IVM) is an assisted reproductive technology with a long and sometimes checked history. It is a minimally invasive technique involving the deliberate collection of immature oocytes...