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Johan Lorenzen

Explore the profile of Johan Lorenzen including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 564
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Recent Articles
1.
Beau-Lejdstrom R, Hong L, Garcia de Albeniz X, Floricel F, Lorenzen J, Bonfitto F, et al.
Drug Saf . 2022 Jun; 45(7):781-790. PMID: 35761158
Introduction: Acute kidney injury is an expected adverse drug reaction listed in the European Union (EU) Summary of Product Characteristics (SmPC) for levetiracetam, one of the most widely used modern...
2.
Puthanveetil P, Gutschner T, Lorenzen J
Hypertens Res . 2019 Dec; 43(5):372-379. PMID: 31853043
Cardiovascular and renal complications cover a wide array of diseases. The most commonly known overlapping complications include cardiac and renal fibrosis, cardiomyopathy, cardiac hypertrophy, hypertension, and cardiorenal failure. The known...
3.
Madadi S, Schwarzenbach H, Lorenzen J, Soleimani M
Cell Mol Life Sci . 2019 May; 76(18):3497-3514. PMID: 31089747
Accurate determination of microRNA expression levels is a prerequisite in using these small non-coding RNA molecules as novel biomarkers in disease diagnosis and prognosis. Quantitative PCR is the method of...
4.
Muller-Deile J, Dannenberg J, Liu P, Lorenzen J, Nystrom J, Thum T, et al.
J Cell Mol Med . 2019 Apr; 23(6):3927-3939. PMID: 30950172
MicroRNAs (miRs) are small non-coding RNAs that regulate gene expression in physiological processes as well as in diseases. Currently miRs are already used to find novel mechanisms involved in diseases...
5.
Kolling M, Genschel C, Kaucsar T, Hubner A, Rong S, Schmitt R, et al.
Sci Rep . 2018 Feb; 8(1):3438. PMID: 29467431
Renal ischemia-reperfusion (I/R) injury is a major cause of acute kidney injury (AKI). Non-coding RNAs are crucially involved in its pathophysiology. We identified hypoxia-induced long non-coding RNA Malat1 (Metastasis Associated...
6.
Muller-Deile J, Gellrich F, Schenk H, Schroder P, Nystrom J, Lorenzen J, et al.
Cell Physiol Biochem . 2016 Dec; 40(5):819-830. PMID: 27941332
Background: TGF-β is known as an important stress factor of podocytes in glomerular diseases. Apart from activation of direct pro-apoptotic pathways we wanted to analyze micro-RNA (miRs) driven regulation of...
7.
Busch M, Nadal J, Schmid M, Paul K, Titze S, Hubner S, et al.
BMC Nephrol . 2016 Jun; 17(1):59. PMID: 27286816
Background: Diabetes mellitus (DM) is the leading cause of end-stage renal disease. Little is known about practice patterns of anti-diabetic therapy in the presence of chronic kidney disease (CKD) and...
8.
Schmidt J, Lorenzen J, Chatzikyrkou C, Lichtinghagen R, Kielstein J
BMC Pharmacol Toxicol . 2014 Sep; 15:49. PMID: 25193402
Background: Lithium intoxication has potentially fatal neurologic and cardiac side effects. Extracorporeal removal can therefore be lifesaving. The dialysance of lithium is high as it is a small molecule. Comparable...
9.
Martino F, Lorenzen J, Schmidt J, Schmidt M, Broll M, Gorzig Y, et al.
PLoS One . 2012 Jun; 7(6):e38269. PMID: 22715378
Background: Circulating microRNAs are stably detectable in serum/plasma and other body fluids. In patients with acute kidney injury on dialysis therapy changes of miRNA patterns had been detected. It remains...
10.
Lorenzen J, Kumarswamy R, Dangwal S, Thum T
RNA Biol . 2012 Jun; 9(6):820-7. PMID: 22664916
Diabetes mellitus due to its high prevalence and associated complications is a major socioeconomic health problem. Diabetes is characterized by multiple macro- and microvascular complications (e.g. diabetic nephropathy, cardiomyopathy, neuropathy,...