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Joerg Christian Tonn

Explore the profile of Joerg Christian Tonn including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 753
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Recent Articles
11.
Stupp R, Hegi M, Gorlia T, Erridge S, Perry J, Hong Y, et al.
Lancet Oncol . 2014 Aug; 15(10):1100-8. PMID: 25163906
Background: Cilengitide is a selective αvβ3 and αvβ5 integrin inhibitor. Data from phase 2 trials suggest that it has antitumour activity as a single agent in recurrent glioblastoma and in...
12.
Strupp M, Stuckrad-Barre S, Brandt T, Tonn J
Neurology . 2013 Feb; 80(7):e77. PMID: 23400324
No abstract available.
13.
Reardon D, Neyns B, Weller M, Tonn J, Nabors L, Stupp R
Future Oncol . 2011 Mar; 7(3):339-54. PMID: 21417900
Cilengitide, a cyclicized arginine-glycine-aspartic acid-containing pentapeptide, potently blocks ανβ3 and ανβ5 integrin activation. Integrins are upregulated in many malignancies and mediate a wide variety of tumor-stroma interactions. Cilengitide and other...
14.
Astner S, Pihusch R, Nieder C, Rachinger W, Lohner H, Tonn J, et al.
Anticancer Res . 2007 Jan; 26(6C):4917-20. PMID: 17214362
Cases of extracranial metastases of glioblastoma multiforme to sites such as bones, spleen, lung, liver and kidneys have been reported but available information about treatment of organ and bone metastases...