Joel O Wertheim
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Explore the profile of Joel O Wertheim including associated specialties, affiliations and a list of published articles.
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129
Citations
5239
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Recent Articles
1.
Havens J, Kosakovsky Pond S, Zehr J, Pekar J, Parker E, Worobey M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060453
Using a phylogenetic framework to characterize natural selection, we investigate the hypothesis that zoonotic viruses require adaptation prior to zoonosis to sustain human-to-human transmission. Examining the zoonotic emergence of Ebola...
2.
Pekar J, Moshiri N, Lemey P, Crits-Christoph A, Debarre F, Goldstein S, et al.
Virus Evol
. 2025 Mar;
11(1):veaf008.
PMID: 40040925
Understanding the genomic diversity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the outset of the coronavirus disease 2019 pandemic can provide insight into the circumstances leading to its...
3.
Billock R, France A, Saduvala N, Panneer N, Hallmark C, Wertheim J, et al.
AIDS
. 2024 Dec;
PMID: 39715047
Objective: To estimate the influence of bursts of rapid HIV transmission on future transmission and describe populations affected by transmission bursts. Design: Phylogenetic analysis of US National HIV Surveillance System...
4.
Crits-Christoph A, Levy J, Pekar J, Goldstein S, Singh R, Hensel Z, et al.
Cell
. 2024 Sep;
187(19):5468-5482.e11.
PMID: 39303692
Zoonotic spillovers of viruses have occurred through the animal trade worldwide. The start of the COVID-19 pandemic was traced epidemiologically to the Huanan Seafood Wholesale Market. Here, we analyze environmental...
5.
Pekar J, Wang Y, Wang J, Shao Y, Taki F, Forgione L, et al.
medRxiv
. 2024 Aug;
PMID: 39132479
The global mpox epidemic in 2022 was likely caused by transmission of mpox virus (MPXV) through sexual contact networks, with New York City (NYC) experiencing the first and largest outbreak...
6.
Weaver S, Davila Conn V, Ji D, Verdonk H, Avila-Rios S, Leigh Brown A, et al.
Front Bioinform
. 2024 Aug;
4():1400003.
PMID: 39086842
Molecular surveillance of viral pathogens and inference of transmission networks from genomic data play an increasingly important role in public health efforts, especially for HIV-1. For many methods, the genetic...
7.
Vasylyeva T, Havens J, Wang J, Luoma E, W Hassler G, Amin H, et al.
PLoS Pathog
. 2024 Jun;
20(6):e1012288.
PMID: 38900824
Socio-economic disparities were associated with disproportionate viral incidence between neighborhoods of New York City (NYC) during the first wave of SARS-CoV-2. We investigated how these disparities affected the co-circulation of...
8.
Carrasco-Hernandez R, Valenzuela-Ponce H, Soto-Nava M, Garcia-Morales C, Matias-Florentino M, Wertheim J, et al.
Epidemics
. 2024 May;
47:100770.
PMID: 38761432
In the context of infectious diseases, the dynamic interplay between ever-changing host populations and viral biology demands a more flexible modeling approach than common fixed correlations. Embracing random-effects regression models...
9.
Magee A, Holbrook A, Pekar J, Caviedes-Solis I, Matsen Iv F, Baele G, et al.
Syst Biol
. 2024 May;
73(3):562-578.
PMID: 38712512
Phylogenetic and discrete-trait evolutionary inference depend heavily on an appropriate characterization of the underlying character substitution process. In this paper, we present random-effects substitution models that extend common continuous-time Markov...
10.
Weaver S, Davila-Conn V, Ji D, Verdonk H, Avila-Rios S, Leigh Brown A, et al.
bioRxiv
. 2024 Apr;
PMID: 38559140
Molecular surveillance of viral pathogens and inference of transmission networks from genomic data play an increasingly important role in public health efforts, especially for HIV-1. For many methods, the genetic...