Joel M Guthridge
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Explore the profile of Joel M Guthridge including associated specialties, affiliations and a list of published articles.
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138
Citations
5263
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Recent Articles
1.
Zaslavsky M, Craig E, Michuda J, Sehgal N, Ram-Mohan N, Lee J, et al.
Science
. 2025 Feb;
387(6736):eadp2407.
PMID: 39977494
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system's own record of antigen exposures encoded by...
2.
Yuan X, Qin X, Takemoto K, Zhao J, Sanderson M, Xu X, et al.
Ann Rheum Dis
. 2025 Feb;
84(2):294-306.
PMID: 39919902
Objective: We assessed the role of a systemic lupus erythematosus causal hypofunctional variant, neutrophil cytosolic factor 1 (NCF1)-p.Arg90His (p.R90H) substitution, in systemic sclerosis (SSc). Methods: Association of NCF1-H90 with SSc...
3.
Cordeiro B, Ahn J, Gawde S, Ucciferri C, Alvarez-Sanchez N, Revelo X, et al.
Cell Metab
. 2024 Aug;
36(10):2298-2314.e11.
PMID: 39168127
Obesity has been implicated in the rise of autoimmunity in women. We report that obesity induces a serum protein signature that is associated with T helper 1 (Th1), interleukin (IL)-17,...
4.
Wiley M, Khatri B, Joachims M, Tessneer K, Stolarczyk A, Rasmussen A, et al.
bioRxiv
. 2024 Jul;
PMID: 39071447
Fine mapping and bioinformatic analysis of the genetic risk association in Sjögren's Disease (SjD) and Systemic Lupus Erythematosus (SLE) identified five common SNPs with functional evidence in immune cell types:...
5.
Fava A, Wagner C, Guthridge C, Kheir J, Macwana S, DeJager W, et al.
Arthritis Rheumatol
. 2024 Jul;
76(11):1611-1622.
PMID: 38962936
Objective: Autoantibodies are a hallmark of lupus nephritis (LN), but their association with LN classes and treatment response are not adequately known. In this study, we quantified circulating autoantibodies in...
6.
Gawde S, Siebert N, Ruprecht K, Kumar G, Ko R, Massey K, et al.
Neurol Neuroimmunol Neuroinflamm
. 2024 Jun;
11(4):e200268.
PMID: 38885457
Background And Objectives: AQP4 antibody-positive NMOSD (AQP4-NMOSD), MOG antibody-associated disease (MOGAD), and seronegative NMOSD (SN-NMOSD) are neuroautoimmune conditions that have overlapping clinical manifestations. Yet, important differences exist in these diseases,...
7.
Carlucci P, Preisinger K, Deonaraine K, Zaminski D, DallEra M, Gold H, et al.
Rheumatology (Oxford)
. 2024 Mar;
64(3):1193-1200.
PMID: 38530774
Objective: Lupus nephritis (LN) can occur as an isolated component of disease activity or be accompanied by diverse extrarenal manifestations. Whether isolated renal disease is sufficient to decrease health-related quality...
8.
Jog N, Wagner C, Aberle T, Chakravarty E, Arriens C, Guthridge J, et al.
Front Immunol
. 2024 Mar;
15():1339250.
PMID: 38524128
Neutrophil dysregulation, particularly of a low-density subset, is associated with systemic lupus erythematosus (SLE); however, the exact role of normal-density neutrophils in SLE remains unknown. This study compares activation and...
9.
Izmirly P, Kim M, Carlucci P, Preisinger K, Cohen B, Deonaraine K, et al.
Arthritis Res Ther
. 2024 Feb;
26(1):54.
PMID: 38378664
Background: Leveraging the Accelerating Medicines Partnership (AMP) Lupus Nephritis (LN) dataset, we evaluated longitudinal patterns, rates, and predictors of response to standard-of-care therapy in patients with lupus nephritis. Methods: Patients...
10.
Chakravarty E, Utset T, Kamen D, Contreras G, McCune W, Aranow C, et al.
Lancet Rheumatol
. 2024 Feb;
6(3):e168-e177.
PMID: 38301682
Background: Mycophenolate mofetil is an immunosuppressant commonly used to treat systemic lupus erythematosus (SLE) and lupus nephritis. It is a known teratogen associated with significant toxicities, including an increased risk...