Joel Lachuer
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Explore the profile of Joel Lachuer including associated specialties, affiliations and a list of published articles.
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60
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1717
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Recent Articles
1.
Villalard B, Boltjes A, Reynaud F, Imbaud O, Thoinet K, Timmerman I, et al.
Nat Commun
. 2024 Nov;
15(1):9570.
PMID: 39500881
Despite their indisputable importance in neuroblastoma (NB) pathology, knowledge of the bases of NB plasticity and heterogeneity remains incomplete. They may be rooted in developmental trajectories of their lineage of...
2.
El Yacoubi M, Altersitz C, Latapie V, Rizkallah E, Arthaud S, Bougarel L, et al.
Neuropsychopharmacology
. 2024 Feb;
49(7):1129-1139.
PMID: 38326457
Treatments are only partially effective in major depressive disorders (MDD) but no biomarker exists to predict symptom improvement in patients. Animal models are essential tools in the development of antidepressant...
3.
Noh H, Anota A, Mongondry R, Meyrand R, Dupuis C, Schiffler C, et al.
BMC Cancer
. 2024 Jan;
24(1):84.
PMID: 38225551
Background: Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15-40 years, with increasing incidence worldwide. About 33 ~ 50% of the patients present with metastatic...
4.
Hemonnot-Girard A, Meersseman C, Pastore M, Garcia V, Linck N, Rey C, et al.
J Neuroinflammation
. 2022 Sep;
19(1):234.
PMID: 36153535
Background: Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD). In parallel, a series of studies showed that, under...
5.
Bellanger A, Le D, Vendrell J, Wierinckx A, Pongor L, Solassol J, et al.
Front Oncol
. 2021 Jul;
11:647269.
PMID: 34277402
Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has...
6.
Gerossier L, Dubois A, Paturel A, Fares N, Cohen D, Merle P, et al.
Clin Res Hepatol Gastroenterol
. 2020 Nov;
45(5):101553.
PMID: 33183998
Background: A promising avenue for cancer treatment is exacerbating the deregulation of the DNA repair machinery that would normally protect the genome. To address the applicability of poly(ADP-ribose) polymerase (PARP)...
7.
Fouret J, Brunet F, Binet M, Aurine N, Enchery F, Croze S, et al.
Front Microbiol
. 2020 Aug;
11:1807.
PMID: 32849415
Indian fruit bats, flying fox was identified as an asymptomatic natural host of recently emerged Nipah virus, which is known to induce a severe infectious disease in humans. The absence...
8.
Robelin P, Tod M, Colomban O, Lachuer J, Ray-Coquard I, de Rauglaudre G, et al.
Gynecol Oncol
. 2020 Jul;
159(1):256-263.
PMID: 32712155
Objective: MicroRNAs (miRNAs) are promising biomarkers in ovarian cancer. Their kinetics during treatment might be useful for monitoring disease burden, and guiding treatments in patients treated with peri-operative chemotherapy and...
9.
Donini C, El Helou M, Wierinckx A, Gyorffy B, Aires S, Escande A, et al.
Front Oncol
. 2020 Jul;
10:712.
PMID: 32670863
It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were...
10.
Berthel E, Vincent A, Eberst L, Torres A, Dacheux E, Rey C, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32290274
BRCA1 inactivation is a hallmark of familial breast cancer, often associated with aggressive triple negative breast cancers. BRCA1 is a tumor suppressor with known functions in DNA repair, transcription regulation,...