Joel L Rosenbaum
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Explore the profile of Joel L Rosenbaum including associated specialties, affiliations and a list of published articles.
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39
Citations
4214
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Recent Articles
1.
Nilsen T, Altman A, Stark B, Feinstein S, Koski R, Mickiewicz C, et al.
RNA
. 2022 Sep;
28(11):1393-1429.
PMID: 36113877
No abstract available.
2.
Long H, Zhang F, Xu N, Liu G, Diener D, Rosenbaum J, et al.
Curr Biol
. 2016 Nov;
26(24):3327-3335.
PMID: 27866888
Primary and motile cilia/flagella function as cellular antennae, receiving signals from the environment and subsequently activating signaling pathways that are critical for cellular homeostasis and differentiation [1-3]. Recent work with...
3.
Wood C, Rosenbaum J
Trends Cell Biol
. 2015 Jan;
25(5):276-85.
PMID: 25618328
The cilium is the site of function for a variety of membrane receptors, enzymes and signal transduction modules crucial for a spectrum of cellular processes. Through targeted transport and selective...
4.
Diener D, Lupetti P, Rosenbaum J
Curr Biol
. 2015 Jan;
25(3):379-384.
PMID: 25578910
The transition zone (TZ) is a specialized region of the cilium characterized by Y-shaped connectors between the microtubules of the ciliary axoneme and the ciliary membrane [1]. Located near the...
5.
Wood C, Rosenbaum J
Curr Biol
. 2014 May;
24(10):1114-20.
PMID: 24814148
The cilium is a specialized extension of the cell in which many specific proteins are admitted and retained, while many others are excluded or expelled. In order to maintain the...
6.
Wood C, Huang K, Diener D, Rosenbaum J
Curr Biol
. 2013 Apr;
23(10):906-11.
PMID: 23623554
The release of membrane vesicles from the surface of cells into their surrounding environment is now recognized as an important pathway for the delivery of proteins to extracellular sites of...
7.
Gupta A, Diener D, Sivadas P, Rosenbaum J, Yang P
J Cell Biol
. 2012 Jul;
198(1):115-26.
PMID: 22753897
LC8 is present in various molecular complexes. However, its role in these complexes remains unclear. We discovered that although LC8 is a subunit of the radial spoke (RS) complex in...
8.
Yuan S, Li J, Diener D, Choma M, Rosenbaum J, Sun Z
Proc Natl Acad Sci U S A
. 2012 Feb;
109(6):2021-6.
PMID: 22308353
The cilium serves as a cellular antenna by coordinating upstream environmental cues with numerous downstream signaling processes that are indispensable for the function of the cell. This role is supported...
9.
Diener D, Yang P, Geimer S, Cole D, Sale W, Rosenbaum J
Cytoskeleton (Hoboken)
. 2011 Jun;
68(7):389-400.
PMID: 21692193
The unicellular alga Chlamydomonas can assemble two 10 μm flagella in 1 h from proteins synthesized in the cell body. Targeting and transporting these proteins to the flagella are simplified...
10.
Kohno T, Wakabayashi K, Diener D, Rosenbaum J, Kamiya R
Cytoskeleton (Hoboken)
. 2011 Mar;
68(4):237-46.
PMID: 21391306
The radial spoke (RS)/central pair (CP) system in cilia and flagella plays an essential role in the regulation of force generation by dynein, the motor protein that drives cilia/flagella movements....