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Joel H Hapke

Explore the profile of Joel H Hapke including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 12
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Recent Articles
1.
Collins D, Hapke J, Aravalli R, Steer C
Hepat Med . 2020 Jul; 12:79-92. PMID: 32607015
Background: Research directed towards drug development, metabolism, and liver functions often utilize primary hepatocytes (PH) for preliminary in vitro studies. Variability in the in vitro functionality of PH and the...
2.
Collins D, Hapke J, Aravalli R, Steer C
PLoS One . 2020 Jun; 15(6):e0234002. PMID: 32497071
Human primary hepatocytes (PHs) are critical to studying liver functions, drug metabolism and toxicity. PHs isolated from livers that are unacceptable for transplantation have limited expansion and culture viability in...
3.
Aravalli R, Collins D, Hapke J, Crane A, Steer C
Hepat Med . 2020 Feb; 12:15-27. PMID: 32104112
Background: Primary human hepatocytes (PHHs) are the ideal candidates for studying critical liver functions such as drug metabolism and toxicity. However, as they are isolated from discarded livers that are...