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Joe Truong Nguyen

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Recent Articles
1.
Chang I, Loo Y, Patel J, Nguyen J, Kim J, Krebsbach P
Front Oncol . 2024 Mar; 14:1375498. PMID: 38532930
mEAK-7 (mammalian EAK-7 or MTOR-associated protein, eak-7 homolog), is an evolutionarily conserved lysosomal membrane protein that is highly expressed in several cancer cells. Multiple recent studies have identified mEAK-7 as...
2.
Nguyen J, Allen C, Dodge J, Van Doorslaer K, McBride A, Pavletic S, et al.
Clin Case Rep . 2021 May; 9(5):e04253. PMID: 34026202
We recently identified and treated a rare case of oral focal epithelial hyperplasia (FEH) in an adult patient with chronic graft-vs-host disease. This is the first report linking KTP laser...
3.
Mendonca D, Nguyen J, Haidar F, Fox A, Ray C, Amatullah H, et al.
Heliyon . 2020 Dec; 6(12):e05734. PMID: 33364499
Regulation of mTOR signaling depends on an intricate interplay of post-translational protein modification. Recently, mEAK-7 (mTOR associated protein, eak-7 homolog) was identified as a positive activator of mTOR signaling via...
4.
Nguyen J, Haidar F, Fox A, Ray C, Mendonca D, Kim J, et al.
iScience . 2019 Jul; 17:190-207. PMID: 31288154
MTOR associated protein, eak-7 homolog (mEAK-7), activates mechanistic target of rapamycin (mTOR) signaling in human cells through an alternative mTOR complex to regulate S6K2 and 4E-BP1. However, the role of...
5.
Nguyen J, Ray C, Fox A, Mendonca D, Kim J, Krebsbach P
Sci Adv . 2018 May; 4(5):eaao5838. PMID: 29750193
Nematode EAK-7 (enhancer-of--1-7) regulates dauer formation and controls life span; however, the function of the human ortholog mammalian EAK-7 (mEAK-7) is unknown. We report that mEAK-7 activates an alternative mechanistic/mammalian...