Joe Shuga
Overview
Explore the profile of Joe Shuga including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
5454
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0
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Recent Articles
1.
Overbey E, Kim J, Tierney B, Park J, Houerbi N, Lucaci A, et al.
Nature
. 2024 Jun;
632(8027):1145-1154.
PMID: 38862028
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space. Yet...
2.
Fang L, Zhu B, Zhao Y, Chen W, Yang Z, Kerrigan L, et al.
Nat Biotechnol
. 2021 Sep;
39(9):1151-1160.
PMID: 34504347
The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms limits the implementation and uptake of cancer genomics....
3.
Pollen A, Bhaduri A, Andrews M, Nowakowski T, Meyerson O, Mostajo-Radji M, et al.
Cell
. 2019 Feb;
176(4):743-756.e17.
PMID: 30735633
Direct comparisons of human and non-human primate brains can reveal molecular pathways underlying remarkable specializations of the human brain. However, chimpanzee tissue is inaccessible during neocortical neurogenesis when differences in...
4.
Nowakowski T, Bhaduri A, Pollen A, Alvarado B, Mostajo-Radji M, Di Lullo E, et al.
Science
. 2017 Dec;
358(6368):1318-1323.
PMID: 29217575
Systematic analyses of spatiotemporal gene expression trajectories during organogenesis have been challenging because diverse cell types at different stages of maturation and differentiation coexist in the emerging tissues. We identified...
5.
Wiley C, Flynn J, Morrissey C, Lebofsky R, Shuga J, Dong X, et al.
Aging Cell
. 2017 Jul;
16(5):1043-1050.
PMID: 28699239
Senescent cells play important roles in both physiological and pathological processes, including cancer and aging. In all cases, however, senescent cells comprise only a small fraction of tissues. Senescent phenotypes...
6.
Ramalingam N, Fowler B, Szpankowski L, Leyrat A, Hukari K, Maung M, et al.
Front Bioeng Biotechnol
. 2017 Mar;
5:11.
PMID: 28299310
[This corrects the article on p. 70 in vol. 4, PMID: 27709111.].
7.
Zheng G, Terry J, Belgrader P, Ryvkin P, Bent Z, Wilson R, et al.
Nat Commun
. 2017 Jan;
8:14049.
PMID: 28091601
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3' mRNA counting of tens of thousands of single cells...
8.
Ramalingam N, Fowler B, Szpankowski L, Leyrat A, Hukari K, Maung M, et al.
Front Bioeng Biotechnol
. 2016 Oct;
4:70.
PMID: 27709111
The study of single cells has evolved over the past several years to include expression and genomic analysis of an increasing number of single cells. Several studies have demonstrated wide...
9.
Pollen A, Nowakowski T, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas C, et al.
Cell
. 2015 Sep;
163(1):55-67.
PMID: 26406371
Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zone and outer subventricular zone. Although outer subventricular zone radial glia may generate the...
10.
Pollen A, Nowakowski T, Shuga J, Wang X, Leyrat A, Lui J, et al.
Nat Biotechnol
. 2014 Aug;
32(10):1053-8.
PMID: 25086649
Large-scale surveys of single-cell gene expression have the potential to reveal rare cell populations and lineage relationships but require efficient methods for cell capture and mRNA sequencing. Although cellular barcoding...