Joe N Frost
Overview
Explore the profile of Joe N Frost including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
343
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Huang X, Feng D, Mitra S, Andretta E, Hooshdaran N, Ghelani A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975175
Regulatory T (Treg) cells contribute to solid organ cancer progression, except in colorectal cancer (CRC) despite being abundantly present. Here, we demonstrate that two distinct tumoral IL-10⁺ and IL-10⁻ Treg...
2.
Wideman S, Frost J, Richter F, Naylor C, Lopes J, Viveiros N, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011679.
PMID: 37812650
Malaria and iron deficiency are major global health problems with extensive epidemiological overlap. Iron deficiency-induced anaemia can protect the host from malaria by limiting parasite growth. On the other hand,...
3.
Preston A, Frost J, Badat M, Teh M, Armitage A, Norfo R, et al.
bioRxiv
. 2023 Oct;
PMID: 37808769
Generation of mature cells from progenitors requires tight coupling of differentiation and metabolism. During erythropoiesis, erythroblasts are required to massively upregulate globin synthesis then clear extraneous material and enucleate to...
4.
Santosa E, Kim H, Ruckert T, Le Luduec J, Abbasi A, Wingert C, et al.
Nat Immunol
. 2023 Sep;
24(10):1685-1697.
PMID: 37697097
Natural killer (NK) cells are innate cytotoxic lymphocytes with adaptive immune features, including antigen specificity, clonal expansion and memory. As such, NK cells share many transcriptional and epigenetic programs with...
5.
Frost J, Wideman S, Preston A, Teh M, Ai Z, Wang L, et al.
Sci Adv
. 2022 Oct;
8(40):eabq5384.
PMID: 36197985
Low plasma iron (hypoferremia) induced by hepcidin is a conserved inflammatory response that protects against infections but inhibits erythropoiesis. How hypoferremia influences leukocytogenesis is unclear. Using proteomic data, we predicted...
6.
Frost J, Hamilton F, Arnold D, Elvers K, Shah A, Armitage A, et al.
Wellcome Open Res
. 2022 Aug;
7:173.
PMID: 35935705
Marked reductions in serum iron concentrations are commonly induced during the acute phase of infection. This phenomenon, termed hypoferremia of inflammation, leads to inflammatory anemia, but could also have broader...
7.
Preston A, Drakesmith H, Frost J
Immunother Adv
. 2022 Aug;
1(1):ltab007.
PMID: 35919735
Vaccination programmes are critically important to suppress the burden of infectious diseases, saving countless lives globally, as emphasised by the current COVID-19 pandemic. Effective adaptive immune responses are complex processes...
8.
Teh M, Frost J, Armitage A, Drakesmith H
Front Immunol
. 2021 Dec;
12:714613.
PMID: 34880854
Recent findings have shown that iron is a powerful regulator of immune responses, which is of broad importance because iron deficiency is highly prevalent worldwide. However, the underlying reasons of...
9.
Littwitz-Salomon E, Moreira D, Frost J, Choi C, Liou K, Ahern D, et al.
Nat Commun
. 2021 Sep;
12(1):5376.
PMID: 34508086
Natural killer (NK) cells are important early responders against viral infections. Changes in metabolism are crucial to fuel NK cell responses, and altered metabolism is linked to NK cell dysfunction...
10.
Chauveau L, Bridgeman A, Tan T, Beveridge R, Frost J, Rijal P, et al.
EMBO Rep
. 2021 Jun;
22(8):e52447.
PMID: 34142428
Cyclic GMP-AMP (cGAMP) is an immunostimulatory molecule produced by cGAS that activates STING. cGAMP is an adjuvant when administered alongside antigens. cGAMP is also incorporated into enveloped virus particles during...