Joe G Greener
Overview
Explore the profile of Joe G Greener including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
808
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0
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Recent Articles
11.
Greener J, Moffat L, Jones D
Sci Rep
. 2018 Nov;
8(1):16189.
PMID: 30385875
The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and...
12.
Craven G, Affron D, Allen C, Matthies S, Greener J, Morgan R, et al.
Angew Chem Int Ed Engl
. 2018 Feb;
57(19):5257-5261.
PMID: 29480525
Cysteine-reactive small molecules are used as chemical probes of biological systems and as medicines. Identifying high-quality covalent ligands requires comprehensive kinetic analysis to distinguish selective binders from pan-reactive compounds. Quantitative...
13.
Greener J, Sternberg M
Curr Opin Struct Biol
. 2017 Oct;
50:1-8.
PMID: 29080471
Allostery is the functional change at one site on a protein caused by a change at a distant site. In order for the benefits of allostery to be taken advantage...
14.
Greener J, Filippis I, Sternberg M
Structure
. 2017 Feb;
25(3):546-558.
PMID: 28190781
The related concepts of protein dynamics, conformational ensembles and allostery are often difficult to study with molecular dynamics (MD) due to the timescales involved. We present ExProSE (Exploration of Protein...
15.
Greener J, Sternberg M
BMC Bioinformatics
. 2015 Oct;
16:335.
PMID: 26493317
Background: Despite being hugely important in biological processes, allostery is poorly understood and no universal mechanism has been discovered. Allosteric drugs are a largely unexplored prospect with many potential advantages...