Jody Rosenblatt
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Explore the profile of Jody Rosenblatt including associated specialties, affiliations and a list of published articles.
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33
Citations
1297
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Recent Articles
1.
Martin P, Pardo-Pastor C, Gisli Jenkins R, Rosenblatt J
Science
. 2024 Dec;
386(6726):eadp2974.
PMID: 39636982
Although the age of the genome gave us much insight about how our organs fail with disease, it also suggested that diseases do not arise from mutations alone; rather, they...
2.
Bagley D, Russell T, Ortiz-Zapater E, Stinson S, Fox K, Redd P, et al.
Science
. 2024 Apr;
384(6691):66-73.
PMID: 38574138
Asthma is deemed an inflammatory disease, yet the defining diagnostic feature is mechanical bronchoconstriction. We previously discovered a conserved process called cell extrusion that drives homeostatic epithelial cell death when...
3.
Rynne J, Ortiz-Zapater E, Bagley D, Zanin O, Doherty G, Kanabar V, et al.
Front Cell Dev Biol
. 2023 Nov;
11:1241008.
PMID: 37928904
Asthma is the most common chronic inflammatory disease of the airways. The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA...
4.
Pardo-Pastor C, Rosenblatt J
Sci Adv
. 2023 Sep;
9(39):eadi1328.
PMID: 37756411
EGFR-ERK signaling controls cell cycle progression during development, homeostasis, and disease. While EGF ligand and mechanical inputs can activate EGFR-ERK signaling, the molecules linking mechanical force to this axis have...
5.
Bagley D, Russell T, Ortiz-Zapater E, Fox K, Redd P, Joseph M, et al.
bioRxiv
. 2023 Aug;
PMID: 37577550
Asthma is deemed an inflammatory disease, yet the defining diagnostic symptom is mechanical bronchoconstriction. We previously discovered a conserved process that drives homeostatic epithelial cell death in response to mechanical...
6.
Mitchell S, Pardo-Pastor C, Zangle T, Rosenblatt J
bioRxiv
. 2023 Mar;
PMID: 36993671
Epithelial cells work collectively to provide a protective barrier, yet also turn over rapidly by cell death and division. If the number of dying cells does not match those dividing,...
7.
Zulueta-Coarasa T, Fadul J, Ahmed M, Rosenblatt J
iScience
. 2022 Nov;
25(11):105330.
PMID: 36325066
Metastasis is tightly linked with poor cancer prognosis, yet it is not clear how transformed cells become invasive carcinomas. We previously discovered that single KRas-transformed cells can invade directly from...
8.
Ortiz-Zapater E, Bagley D, Hernandez V, Roberts L, Maguire T, Voss F, et al.
Nat Commun
. 2022 Oct;
13(1):6407.
PMID: 36302767
Airway inflammation and remodelling are important pathophysiologic features in asthma and other respiratory conditions. An intact epithelial cell layer is crucial to maintain lung homoeostasis, and this depends on intercellular...
9.
Fadul J, Zulueta-Coarasa T, Slattum G, Redd N, Jin M, Redd M, et al.
Nat Commun
. 2021 Dec;
12(1):7180.
PMID: 34893591
Metastasis is the main cause of carcinoma-related death, yet we know little about how it initiates due to our inability to visualize stochastic invasion events. Classical models suggest that cells...
10.
Zulueta-Coarasa T, Rosenblatt J
Curr Opin Genet Dev
. 2021 Sep;
72:1-7.
PMID: 34560388
Epithelia remove dying or excess cells by extrusion, a process that seamlessly squeezes cells out of the layer without disrupting their barrier function. New studies shed light into the intricate...