Jocelyn C Newton
Overview
Explore the profile of Jocelyn C Newton including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
203
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0
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Recent Articles
1.
Rujas E, Kucharska I, Tan Y, Benlekbir S, Cui H, Zhao T, et al.
Nat Commun
. 2021 Jun;
12(1):3661.
PMID: 34135340
SARS-CoV-2, the virus responsible for COVID-19, has caused a global pandemic. Antibodies can be powerful biotherapeutics to fight viral infections. Here, we use the human apoferritin protomer as a modular...
2.
Newton J, Naik M, Li G, Murphy E, Fawzi N, Sedivy J, et al.
Biophys J
. 2021 Apr;
120(11):2181-2191.
PMID: 33798566
Long interspersed nuclear element-1 (L1) is a retrotransposable element that autonomously replicates in the human genome, resulting in DNA damage and genomic instability. Activation of L1 in senescent cells triggers...
3.
East K, Newton J, Morzan U, Narkhede Y, Acharya A, Skeens E, et al.
J Am Chem Soc
. 2019 Dec;
142(3):1348-1358.
PMID: 31885264
CRISPR-Cas9 is a widely employed genome-editing tool with functionality reliant on the ability of the Cas9 endonuclease to introduce site-specific breaks in double-stranded DNA. In this system, an intriguing allosteric...
4.
Choy M, Yusoff P, Lee I, Newton J, Goh C, Page R, et al.
Cell Rep
. 2015 Jun;
11(12):1885-91.
PMID: 26095357
The attenuation of protein synthesis via the phosphorylation of eIF2α is a major stress response of all eukaryotic cells. The growth-arrest- and DNA-damage-induced transcript 34 (GADD34) bound to the serine/threonine...