Joao M Batista Jr
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Explore the profile of Joao M Batista Jr including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
145
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Recent Articles
1.
Lee E, Sousa V, Mestriner E, Bernardino K, Nascimento I, Batista Jr J
Phys Chem Chem Phys
. 2025 Feb;
27(7):3908-3915.
PMID: 39901786
Furofuran lignans are important chiral secondary metabolites widely distributed in the plant kingdom. Despite extensive biological potential, their absolute configuration assignments are mostly based on empirical comparisons of OR values...
2.
Brito I, Castro Levatti E, Regasini L, Ferreira E, Lopes F, Fernandes J, et al.
Phytochemistry
. 2024 Dec;
231():114360.
PMID: 39672219
As part of our continuous study on the Annonaceae species Porcelia macrocarpa, in the present work, eight chemically related 2-alkyl-3-hydroxy-4-methyl-γ-lactones (1-8) were isolated. Their structures were characterised by NMR, MS,...
3.
Mestriner E, Lee E, Cunha C, Sousa V, Nascimento I, Batista Jr J
Chirality
. 2024 Nov;
36(11):e70003.
PMID: 39505494
Fargesin is an important bioactive furofuran lignan isolated from different plant species. Despite presenting potent biological activities, its stereochemical characterization has relied mostly on empirical correlations of optical rotation, an...
4.
Batista A, Valverde A, Nafie L, Batista Jr J
Chem Commun (Camb)
. 2024 Sep;
60(76):10439-10450.
PMID: 39234927
Secondary metabolites from land and marine (micro)organisms have been at the focus of the drug discovery process for many years. One of the reasons for this success is nature's incredible...
5.
de Amorim M, Schoellhorn S, Barbosa C, Mendes G, Macedo K, Ferreira A, et al.
J Nat Prod
. 2024 Aug;
87(9):2204-2215.
PMID: 39150723
Novel open-chain merocytochalasans, perochalasins A-C (-), containing an unusual N-O six-membered heterocyclic moiety, were isolated from cultures of the marine-derived sp. M16 fungus, along with cytochalasin Z (), cytochalasin Z...
6.
Cunha M, Do Amaral B, Takarada J, Valderrama G, Batista A, Batista Jr J, et al.
Chembiochem
. 2024 Jun;
25(22):e202400506.
PMID: 38923811
Autophagic flux plays a crucial role in various diseases. Recently, the lysosomal ion channel TRPML1 has emerged as a promising target in lysosomal storage diseases, such as mucolipidosis. The discovery...
7.
Batista A, Santos C, de Albuquerque A, Santos Jr F, Garcez F, Batista Jr J
Spectrochim Acta A Mol Biomol Spectrosc
. 2023 Aug;
304:123283.
PMID: 37633100
The ability of nature to produce structurally complex molecules makes the determination of the absolute configuration of natural products a challenging task. Although extensive NMR analysis generally allows for the...
8.
Batista Jr J, Nicu V
Phys Chem Chem Phys
. 2023 Aug;
25(33):22111-22116.
PMID: 37560904
Cyclic peptides are privileged structures in medicinal chemistry; however, their solution-state structure characterization is difficult. Vibrational circular dichroism (VCD) spectroscopy is a powerful alternative to NMR, but requires challenging calculations....
9.
Vermeyen T, Batista A, Valverde A, Herrebout W, Batista Jr J
Phys Chem Chem Phys
. 2023 May;
25(20):13825-13832.
PMID: 37191271
Vibrational circular dichroism (VCD) is one of the most powerful techniques to assess the stereochemistry of chiral molecules in solution state. The need for quantum chemical calculations to interpret experimental...
10.
Gubiani J, Bernardi D, De Paula C, Seleghim M, Ferreira A, Batista A, et al.
Arch Pharm (Weinheim)
. 2022 Jan;
355(4):e2100441.
PMID: 35099085
Microbial strains isolated from extreme and understudied environments, such as caves, are still poorly investigated for the production of bioactive secondary metabolites. Investigation of the ethyl acetate extract from the...