Joanna Pastwinska
Overview
Explore the profile of Joanna Pastwinska including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
152
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Recent Articles
1.
Karas K, Pastwinska J, Salkowska A, Karwaciak I, Bachorz R, Ratajewski M
Immunol Cell Biol
. 2025 Jan;
103(3):317-327.
PMID: 39853787
AT7519, which inhibits multiple cyclin-dependent kinases, has been extensively investigated in various types of cancer cells. Previous studies have demonstrated the ability of this molecule to suppress the expression of...
2.
Karas K, Pastwinska J, Salkowska A, Karwaciak I, Ratajewski M
Biochem Biophys Rep
. 2024 Sep;
40:101827.
PMID: 39328838
Mutations in the ganglioside-induced differentiation-associated protein 1 () gene are linked to Charcot-Marie-Tooth (CMT) disease, a hereditary neurodegenerative condition. The protein encoded by this gene is involved in mitochondrial fission...
3.
Pastwinska J, Karwaciak I, Karas K, Salkowska A, Chalaskiewicz K, Strapagiel D, et al.
Immunohorizons
. 2024 Sep;
8(9):606-621.
PMID: 39240270
The human body harbors a substantial population of bacteria, which may outnumber host cells. Thus, there are multiple interactions between both cell types. Given the common presence of Staphylococcus aureus...
4.
Karwaciak I, Pastwinska J, Salkowska A, Bachorz R, Ratajewski M
Arch Biochem Biophys
. 2024 Jul;
759:110085.
PMID: 38971421
Cardiac glycosides, derived from plants and animals, have been recognized since ancient times. These substances hinder the function of the sodium-potassium pump within eukaryotic cells. Many reports have shown that...
5.
Bachorz R, Pastwinska J, Nowak D, Karas K, Karwaciak I, Ratajewski M
Comput Struct Biotechnol J
. 2023 Nov;
21:5491-5505.
PMID: 38022699
In this work, we developed and applied a computational procedure for creating and validating predictive models capable of estimating the biological activity of ligands. The combination of modern machine learning...
6.
Pastwinska J, Karwaciak I, Karas K, Bachorz R, Ratajewski M
Biochim Biophys Acta Rev Cancer
. 2023 Nov;
1878(6):189021.
PMID: 37951483
RORγT is a transcription factor that directs the development of Th17 lymphocytes and other IL-17-expressing cells (e.g., Tc17 and ILC3 cells). These cells are involved in the body's defense against...
7.
Karas K, Karwaciak I, Chalaskiewicz K, Salkowska A, Pastwinska J, Bachorz R, et al.
Biomed Pharmacother
. 2023 Jun;
164:115002.
PMID: 37311277
Hepatocellular carcinoma (HCC) is one of the most common cancerous tumors and one of the leading causes of death among cancer-related disorders. Chemotherapy is ineffective in HCC patients, and the...
8.
Chalaskiewicz K, Karas K, Zaklos-Szyda M, Karwaciak I, Pastwinska J, Koziolkiewicz M, et al.
Eur J Pharmacol
. 2023 Apr;
949:175728.
PMID: 37062501
GLUT5, a key protein encoded by the SLC2A5 gene, is involved in the uptake of fructose from the intestine. Currently, with the increased consumption of this sugar and the associated...
9.
Pastwinska J, Karas K, Karwaciak I, Ratajewski M
Biochim Biophys Acta Rev Cancer
. 2022 Jun;
1877(4):188754.
PMID: 35772580
Melanoma is considered one of the most aggressive skin cancers. It spreads and metastasizes quickly and is intrinsically resistant to most conventional chemotherapeutics, thereby presenting a challenge to researchers and...
10.
Karwaciak I, Karas K, Salkowska A, Pastwinska J, Ratajewski M
Molecules
. 2022 Jun;
27(12).
PMID: 35744777
The COVID-19 pandemic, caused by the rapidly spreading SARS-CoV-2 virus, led to the unprecedented mobilization of scientists, resulting in the rapid development of vaccines and potential pharmaceuticals. Although COVID-19 symptoms...