Joanna K Lempiainen
Overview
Explore the profile of Joanna K Lempiainen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
89
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Valima E, Varis V, Bureiko K, Lempiainen J, Schroderus A, Oksa L, et al.
Oncogene
. 2025 Feb;
PMID: 39953147
Glucocorticoids are a mainstay in the treatment of B-cell acute lymphoblastic leukemia (B-ALL). The glucocorticoid receptor (GR), a ligand-activated transcription factor (TF), mediates their actions. Chromatin occupancy, chromatin-protein networks (chromatomes)...
2.
Zahn E, Xie Y, Liu X, Karki R, Searfoss R, de Luna Vitorino F, et al.
Mol Cell Proteomics
. 2024 Dec;
24(1):100897.
PMID: 39708910
Histone post-translational modifications (PTMs) regulate gene expression patterns through epigenetic mechanisms. The five histone proteins (H1, H2A, H2B, H3, and H4) are extensively modified, with over 75 distinct modification types...
3.
Xie Y, de Luna Vitorino F, Chen Y, Lempiainen J, Zhao C, Steinbock R, et al.
Chem Commun (Camb)
. 2023 Oct;
59(83):12499-12502.
PMID: 37786919
The interest in MS-based analysis of modified nucleic acids is increasing due to the application of nucleic acids in therapeutics. However, there are few available integrated platforms for characterizing nucleic...
4.
Lempiainen J, Garcia B
Biochem J
. 2023 Jan;
480(1):57-85.
PMID: 36630129
Epigenetics, the inheritance of genomic information independent of DNA sequence, controls the interpretation of extracellular and intracellular signals in cell homeostasis, proliferation and differentiation. On the chromatin level, signal transduction...
5.
Manjur A, Lempiainen J, Malinen M, Varjosalo M, Palvimo J, Niskanen E
J Steroid Biochem Mol Biol
. 2021 Mar;
210:105873.
PMID: 33722704
Glucocorticoid (GC) receptor (GR) is a key transcription factor (TF) that regulates vital metabolic and anti-inflammatory processes. We have identified BCL6 corepressor (BCOR) as a dexamethasone-stimulated interaction partner of GR....
6.
Paakinaho V, Lempiainen J, Sigismondo G, Niskanen E, Malinen M, Jaaskelainen T, et al.
Nucleic Acids Res
. 2021 Feb;
49(4):1951-1971.
PMID: 33524141
Glucocorticoid receptor (GR) is an essential transcription factor (TF), controlling metabolism, development and immune responses. SUMOylation regulates chromatin occupancy and target gene expression of GR in a locus-selective manner, but...
7.
Lempiainen J, Manjur A, Malinen M, Ketola K, Niskanen E, Palvimo J
Oncogene
. 2020 Jan;
39(11):2391-2407.
PMID: 31925334
We have identified BCL6 corepressor (BCOR) as a hormone-dependent interaction partner of androgen receptor (AR), a key transcription factor in the development of normal and cancerous prostate. BCOR is often...
8.
Manjur A, Lempiainen J, Malinen M, Palvimo J, Niskanen E
J Steroid Biochem Mol Biol
. 2019 May;
192:105382.
PMID: 31145973
IRF2BP2 (interferon regulatory factor-2 binding protein-2) is an uncharacterized interaction partner of glucocorticoid (GC) receptor (GR), an anti-inflammatory and metabolic transcription factor. Here, we show that GC changes the chromatin...
9.
Lempiainen J, Niskanen E, Vuoti K, Lampinen R, Goos H, Varjosalo M, et al.
Mol Cell Proteomics
. 2017 Jun;
16(8):1462-1474.
PMID: 28611094
Glucocorticoid receptor (GR) and androgen receptor (AR) are steroid-inducible transcription factors (TFs). The GR and the AR are central regulators of various metabolic, homeostatic and differentiation processes and hence important...