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Joanna C Neill

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Articles 48
Citations 1106
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Recent Articles
1.
McCrone P, Fisher H, Knight C, Harding R, Schlag A, Nutt D, et al.
Psychol Med . 2023 Jun; 53(16):7619-7626. PMID: 37264950
Background: There is growing evidence to support the use of the psychedelic drug psilocybin for difficult-to-treat depression. This paper compares the cost-effectiveness of psilocybin-assisted psychotherapy (PAP) with conventional medication, cognitive...
2.
Brown J, Grayson B, Neill J, Harte M, Wall M, Ngomba R
Cells . 2023 Mar; 12(6). PMID: 36980260
The cognitive deficits of schizophrenia are linked to imbalanced excitatory and inhibitory signalling in the prefrontal cortex (PFC), disrupting gamma oscillations. We previously demonstrated that two mGlu5 receptor-positive allosteric modulators...
3.
Woods R, Lorusso J, Harris I, Kowash H, Murgatroyd C, Neill J, et al.
Biomolecules . 2023 Mar; 13(3). PMID: 36979424
Exposure to maternal immune activation (MIA) in utero significantly elevates the risk of developing schizophrenia and other neurodevelopmental disorders. To understand the biological mechanisms underlying the link between MIA and...
4.
Potter H, Kowash H, Woods R, Revill G, Grime A, Deeney B, et al.
Brain Behav Immun . 2022 Dec; 108:162-175. PMID: 36503051
Exposure to inflammatory stressors during fetal development is a major risk factor for neurodevelopmental disorders (NDDs) in adult offspring. Maternal immune activation (MIA), induced by infection, causes an acute increase...
5.
Lorusso J, Woods R, McEwan F, Glazier J, Neill J, Harte M, et al.
Brain Behav Immun Health . 2022 Sep; 25:100514. PMID: 36177307
Schizophrenia and other neurodevelopmental disorders often have very heterogeneous symptoms, especially regarding cognition: while some individuals may exhibit deficient cognition, others are relatively unaffected. Studies using developmental animal models often...
6.
Kowash H, Potter H, Woods R, Ashton N, Hager R, Neill J, et al.
Clin Sci (Lond) . 2022 Jul; 136(15):1117-1137. PMID: 35852150
Maternal infection during pregnancy increases the offspring risk of developing a variety of neurodevelopmental disorders (NDDs), including schizophrenia. While the mechanisms remain unclear, dysregulation of placental function is implicated. We...
7.
Williams J, Burgess S, Suckling J, Lalousis P, Batool F, Griffiths S, et al.
JAMA Psychiatry . 2022 Mar; 79(5):498-507. PMID: 35353173
Importance: Previous in vitro and postmortem research suggests that inflammation may lead to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range of neuropsychiatric disorders. Objective:...
8.
Brown J, Iacovelli L, Di Cicco G, Grayson B, Rimmer L, Fletcher J, et al.
Neuropharmacology . 2022 Feb; 208:108982. PMID: 35151699
In schizophrenia, mGlu5 receptor hypofunction has been linked with neuropathology and cognitive deficits, making it an attractive therapeutic target. The cognitive impairment associated with schizophrenia remains an unmet clinical need,...
9.
Gonda X, Dome P, Neill J, Tarazi F
CNS Spectr . 2021 Sep; 28(1):6-15. PMID: 34588093
Treatment of major depressive disorder (MDD) including treatment-resistant depression (TRD) remains a major unmet need. Although there are several classes of dissimilar antidepressant drugs approved for MDD, the current drugs...
10.
Hojlund M, Kemp A, Haddad P, Neill J, Correll C
Lancet Psychiatry . 2021 Aug; 8(9):748-749. PMID: 34419176
No abstract available.