Joana Caldeira
Overview
Explore the profile of Joana Caldeira including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
536
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0
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Recent Articles
1.
Ribeiro-Machado C, Santos S, Amaral I, Caldeira J, Pereira P, Barbosa M, et al.
NPJ Regen Med
. 2023 Jul;
8(1):34.
PMID: 37429889
Intervertebral disc (IVD) degeneration and herniation is a leading cause of disability globally and a large unmet clinical need. No efficient non-surgical therapy is available, and there is an urgency...
2.
Molinos M, Fiordalisi M, Caldeira J, Almeida C, Barbosa M, Goncalves R
Aging Cell
. 2023 May;
22(8):e13873.
PMID: 37254638
Aging is one of the major etiological factors driving intervertebral disc (IVD) degeneration, the main cause of low back pain. The nucleus pulposus (NP) includes a heterogeneous cell population, which...
3.
Fiordalisi M, Ferreira J, Pinto M, Ribeiro-Machado C, Pinto M, Oliveira M, et al.
Biomater Adv
. 2022 Nov;
143:213192.
PMID: 36403438
With the lack of effective treatments for low back pain, the use of extracellular matrix (ECM)-based biomaterials have emerged with undeniable promise for IVD regeneration. Decellularized scaffolds can recreate an...
4.
Caldeira J, Celiz A, Newell N
J Mech Behav Biomed Mater
. 2022 Mar;
129:105150.
PMID: 35272150
Intervertebral disc (IVD) degeneration has been linked to Low Back Pain (LBP) which affects over 80% of the population ranking first in terms of disability worldwide. Degeneration progresses with age...
5.
Fiordalisi M, Silva A, Barbosa M, Goncalves R, Caldeira J
Trends Biotechnol
. 2020 May;
38(9):947-951.
PMID: 32466967
In the last decade, intervertebral disc (IVD) decellularization has gained significant attention for tissue regenerative purposes as a successful therapeutic alternative for low back pain (LBP). We discuss the recent...
6.
Caldeira J, Santa C, Osorio H, Molinos M, Manadas B, Goncalves R, et al.
Sci Rep
. 2017 Sep;
7(1):11629.
PMID: 28912585
Intervertebral disc (IVD) degeneration is often the cause of low back pain. Degeneration occurs with age and is accompanied by extracellular matrix (ECM) depletion, culminating in nucleus pulpous (NP) extrusion...
7.
Antunes J, Leite Pereira C, Teixeira G, Silva R, Caldeira J, Grad S, et al.
J Mater Sci Mater Med
. 2016 Nov;
28(1):6.
PMID: 27885573
Intervertebral disc (IVD) degeneration often leads to low back pain, which is one of the major causes of disability worldwide, affecting more than 80% of the population. Although available treatments...
8.
Leite Pereira C, Teixeira G, Ribeiro-Machado C, Caldeira J, Costa M, Figueiredo F, et al.
Sci Rep
. 2016 Sep;
6:33836.
PMID: 27652931
Intervertebral disc (IVD) degeneration is characterized by significant biochemical and histomorphological alterations, such as loss of extracellular matrix (ECM) integrity, by abnormal synthesis of ECM main components, resultant from altered...
9.
Caldeira J, Figueiredo J, Bras-Pereira C, Carneiro P, Moreira A, Pinto M, et al.
Hum Mol Genet
. 2015 Aug;
24(20):5891-900.
PMID: 26246502
Epithelial-cadherin (Ecad) deregulation affects cell-cell adhesion and results in increased invasiveness of distinct human carcinomas. In gastric cancer, loss of Ecad expression is a common event and is associated with...
10.
Molinos M, Almeida C, Caldeira J, Cunha C, Goncalves R, Barbosa M
J R Soc Interface
. 2015 Jun;
12(108):20150429.
PMID: 26040602
No abstract available.