Joana Caetano-Lopes
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Explore the profile of Joana Caetano-Lopes including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Miao K, Cozzone A, Caetano-Lopes J, Harris M, Fisher S
Front Endocrinol (Lausanne)
. 2022 Nov;
13:969481.
PMID: 36387889
Efforts to understand the morphogenesis of complex craniofacial structures have largely focused on the role of chondrocytes and osteoblasts. Along with these bone-creating cells, bone-resorbing osteoclasts are critical in homeostasis...
2.
Caetano-Lopes J, Henke K, Urso K, Duryea J, Charles J, Warman M, et al.
Development
. 2020 May;
147(10).
PMID: 32423978
No abstract available.
3.
Li C, Barton C, Henke K, Daane J, Treaster S, Caetano-Lopes J, et al.
Elife
. 2020 Jan;
9.
PMID: 31985398
The use of genetics has been invaluable in defining the complex mechanisms of aging and longevity. Zebrafish, while a prominent model for vertebrate development, have not been used systematically to...
4.
Caetano-Lopes J, Henke K, Urso K, Duryea J, Charles J, Warman M, et al.
Development
. 2020 Jan;
147(2).
PMID: 31932352
Evolution is replete with reuse of genes in different contexts, leading to multifunctional roles of signaling factors during development. Here, we explore osteoclast regulation during skeletal development through analysis of...
5.
Rodrigues A, Eusebio M, Rodrigues A, Caetano-Lopes J, Lopes I, Lopes A, et al.
JBMR Plus
. 2019 Aug;
3(7):e10179.
PMID: 31372588
There are currently no robust noninvasive markers of fragility fractures. Secreted frizzled related protein-1 (sFRP-1), dickkopf-related protein 1 (DKK1) and DKK2, and sclerostin (SOST) inhibit Wnt signaling and interfere with...
6.
Bird I, Kim S, Schweppe D, Caetano-Lopes J, Robling A, Charles J, et al.
Development
. 2017 Nov;
145(1).
PMID: 29180569
Inactivating mutations in the ubiquitously expressed membrane trafficking component GMAP-210 (encoded by ) cause achondrogenesis type 1A (ACG1A). ACG1A is surprisingly tissue specific, mainly affecting cartilage development. Bone development is...
7.
Perpetuo I, Caetano-Lopes J, Rodrigues A, Campanilho-Marques R, Ponte C, Canhao H, et al.
RMD Open
. 2017 Sep;
3(1):e000365.
PMID: 28955481
Objective: Rheumatoid arthritis (RA) is a systemic, immune-mediated inflammatory disease that ultimately leads to bone erosions and joint destruction. Methotrexate (MTX) slows bone damage but the mechanism by which it...
8.
Rees H, Komor A, Yeh W, Caetano-Lopes J, Warman M, Edge A, et al.
Nat Commun
. 2017 Jun;
8:15790.
PMID: 28585549
We recently developed base editing, a genome-editing approach that enables the programmable conversion of one base pair into another without double-stranded DNA cleavage, excess stochastic insertions and deletions, or dependence...
9.
Perpetuo I, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Khmelinskii N, et al.
Front Med (Lausanne)
. 2017 Apr;
4:38.
PMID: 28405583
[This corrects the article on p. 5 in vol. 4, PMID: 28191455.].
10.
Perpetuo I, Caetano-Lopes J, Rodrigues A, Campanilho-Marques R, Ponte C, Canhao H, et al.
Biomed Res Int
. 2017 Mar;
2017:2690402.
PMID: 28286757
. Tumor necrosis factor (TNF) increases circulating osteoclast (OC) precursors numbers by promoting their proliferation and differentiation. The aim of this study was to assess the effect of TNF inhibitors...