Joana B Melo
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Explore the profile of Joana B Melo including associated specialties, affiliations and a list of published articles.
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41
Citations
306
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Recent Articles
1.
Liehr T, Ziegler M, Person L, Kankel S, Padutsch N, Weise A, et al.
Front Genet
. 2024 Jan;
14:1293652.
PMID: 38174048
With only 39 reported cases in the literature, carriers of a small supernumerary marker chromosome (sSMC) derived from chromosome 11 represent an extremely rare cytogenomic condition. Herein, we present a...
2.
Ferreira D, Santos-Pereira C, Costa M, Afonso J, Yang S, Hensel J, et al.
Biomater Adv
. 2023 Oct;
154:213643.
PMID: 37778291
Triple negative breast cancer (TNBC) is a highly heterogenous disease not sensitive to endocrine or HER2 therapy and standardized treatment regimens are still missing. Therefore, development of novel TNBC treatment...
3.
Valerio-Fernandes A, Fonseca N, Goncalves N, Cruz A, Pereira M, Gregorio A, et al.
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565346
Notwithstanding the advances in the treatment of lung cancer with immune checkpoint inhibitors, the high percentage of non-responders supports the development of novel anticancer treatments. Herein, the expression of the...
4.
Cruz A, Fonseca N, Malheiro A, Melo J, Gaspar M, Fernandes R, et al.
Eur J Pharm Biopharm
. 2022 Feb;
172:61-77.
PMID: 35104605
One of the major assets of anticancer nanomedicine is the ability to co-deliver drug combinations, as it enables targeting of different cellular populations and/or signaling pathways implicated in tumorigenesis and...
5.
Lopes S, Mesquita-Bastos J, Garcia C, Bertoquini S, Ribau V, Teixeira M, et al.
JAMA Cardiol
. 2021 Aug;
6(11):1317-1323.
PMID: 34347008
Importance: Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy. Objective: To determine whether an aerobic exercise...
6.
Cruz A, Caleiras M, Fonseca N, Goncalves N, Mendes V, Sampaio S, et al.
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34207464
Targeting multiple cellular populations is of high therapeutic relevance for the tackling of solid tumors heterogeneity. Herein, the ability of pegylated and pH-sensitive liposomes, functionalized with the nucleolin-binding F3 peptide...
7.
Marques A, Resende R, Silva D, Batista M, Pereira D, Wildenberg B, et al.
Biomedicines
. 2021 Jun;
9(5).
PMID: 34066918
This study aims to evaluate whether mitochondrial changes occur in the early stages of bipolar disorder (BD). Using fibroblasts derived from BD patients and matched controls, the levels of proteins...
8.
Jesus-Ribeiro J, Pereira C, Robalo C, Pereira D, Duro D, Ramos F, et al.
Oxf Med Case Reports
. 2021 May;
2021(5):omab027.
PMID: 34055363
Germline and 2-hit brain somatic variants in gene, a negative regulator of the mammalian target of rapamycin (mTOR) pathway, are increasingly recognized in patients with focal cortical dysplasia (FCD). Next-generation...
9.
Wafa A, Jarjour R, Alolabi D, Liehr T, Hamdan O, Melo J, et al.
Mol Cytogenet
. 2020 Sep;
13:44.
PMID: 32944079
Background: B cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood, with, after corresponding treatment, an overall complete remission rate of 90%. Approximately 75% of B-ALL...
10.
de Breuk A, Acar I, Kersten E, Schijvenaars M, Colijn J, Haer-Wigman L, et al.
Ophthalmology
. 2020 Jul;
128(11):1604-1617.
PMID: 32717343
Purpose: To develop a genotype assay to assess associations with common and rare age-related macular degeneration (AMD) risk variants, to calculate an overall genetic risk score (GRS), and to identify...