Joan K Ho
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Explore the profile of Joan K Ho including associated specialties, affiliations and a list of published articles.
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7
Citations
32
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Recent Articles
1.
Al-Wassiti H, Fabb S, Grimley S, Kochappan R, Ho J, Wong C, et al.
Mol Ther Methods Clin Dev
. 2024 Dec;
32(4):101380.
PMID: 39687732
We investigated mRNA vaccines encoding a membrane-anchored receptor-binding domain (RBD), each a fusion of a variant RBD, the transmembrane (TM) and cytoplasmic tail fragments of the severe acute respiratory syndrome...
2.
Sibuea S, Ho J, Pouton C, Haynes J
Front Cell Dev Biol
. 2023 Feb;
11:1111705.
PMID: 36819101
The generation of midbrain dopaminergic neurons (mDAs) from pluripotent stem cells (hPSC) holds much promise for both disease modelling studies and as a cell therapy for Parkinson's disease (PD). Generally,...
3.
Haynes J, Sibuea S, Aguiar A, Li F, Ho J, Pouton C
PLoS One
. 2021 Dec;
16(12):e0261730.
PMID: 34941945
In this study we investigate how β-catenin-dependent WNT signalling impacts midbrain dopaminergic neuron (mDA) specification. mDA cultures at day 65 of differentiation responded to 25 days of the tankyrase inhibitor...
4.
Ho J, White P, Pouton C
Mol Ther Nucleic Acids
. 2018 Sep;
12:504-517.
PMID: 30195787
Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA vaccines. With ease of manufacture and...
5.
Haynes J, Selby J, Vandekolk T, Abad I, Ho J, Lieuw W, et al.
J Pharmacol Exp Ther
. 2018 Aug;
367(2):335-347.
PMID: 30104322
Renal podocyte survival depends upon the dynamic regulation of a complex cell architecture that links the glomerular basement membrane to integrins, ion channels, and receptors. Alport syndrome is a heritable...
6.
Sinha S, Kuo C, Ho J, White P, Jazayeri J, Pouton C
Vaccine
. 2017 Aug;
35(38):5115-5122.
PMID: 28822642
In this study we determined the in vivo activity of model ovalbumin vaccines delivered by direct intramuscular delivery of plasmid DNA or oral delivery using a recombinant suicidal Listeria monocytogenes...
7.
Ho J, White P, Pouton C
Mol Ther Nucleic Acids
. 2016 Oct;
5(10):e371.
PMID: 27701400
Analysis of the tissue distribution of plasmid DNA after administration of nonviral gene delivery systems is best accomplished using quantitative real-time polymerase chain reaction (qPCR), although published strategies do not...